| Acronym | Definition |
|---|
| SER | Service |
| SER | Series |
| SER | Serial |
| SER | Serine (amino acid) |
| SER | Sermon |
| SER | Serbian (language) |
| SER | Serial Number |
| SER | Sociaal-Economische Raad |
| SER | SIP Express Router |
| SER | Society for Ecological Restoration |
| SER | Southeast Region |
| SER | Safety Evaluation Report (US Department of Energy) |
| SER | Smooth Endoplasmic Reticulum |
| SER | Southeast Region (NPS) |
| SER | Soft Error Rate (data storage/retrieval) |
| SER | Symbol Error Rate (similar to BER) |
| SER | South Eastern Railway |
| SER | Servicios Educativos Rurales (Spanish: Rural Education Service; Peru) |
| SER | Society for Epidemiologic Research |
| SER | Sociedad Española de Radiodifusión (Spanish Radio Society) |
| SER | Statistical Error |
| SER | Structural Engineer of Record |
| SER | Sequence of Events Recorder |
| SER | Sentence Error Rate (machine translation evaluation) |
| SER | Spherical Equivalent Refraction |
| SER | System Evaluation Report |
| SER | Sequence of Events Recording |
| SER | Supination External Rotation (type of fracture) |
| SER | Satellite Equipment Room |
| SER | Foundation for Subjective Experience and Research |
| SER | Staples Easy Rebate |
| SER | Single Electron Response (photomultiplier parameter) |
| SER | Southern European Region |
| SER | Systems Engineering Report |
| SER | Search Engine Recognition |
| SER | Shemale Erotic Review |
| SER | System Evaluation Record |
| SER | Shore Establishment Realignment |
| SER | SATCOM Equipment Report |
| SER | Subscriber Edge Router (Shasta Networks) |
| SER | Support Equipment Requirement |
| SER | Single Event Upset Ratio |
| SER | Software-Engineering Rodinger GmbH (Seligenstadt, Germany) |
| SER | System Evolution Record |
| SER | Simultaneous Electrolytic Recovery (gold processing) |
| SER | System Element Review |
| SER | Selected Early Release |
| SER | Skin-Effect Range (microstrip lines) |
| SER | Support Equipment Requirements Sheet |
| SER | Supportability Evaluation Report |
| SER | Société d'Evaluation Rwandaise |