Until the present time, a total of 19 gene defects including 7 gene mutations leading to congenital neutropenia (ELANE; CXCR4, SBDS
, PT14, HAX1, G6PC3, RUNX1) and different genetic diseases accompanied by neutropenias have been identified (12).
Mutations in SBDS are associated with Shwachman-Diamond syndrome.
Novel SBDS mutations caused by gene conversion in Japanese patients with Shwachman-Diamond syndrome.
Structural and mutational analysis of the SBDS protein family.
2 LYST syndrome Cohen syndrome 8q22-q23 COH1 Griscelli syndrome 15q21 RAB27A Type 2 Shwachman-Diamond 7q11 SBDS syndrome Cartilage hair 9p21-p12 RMRP hypoplasia Barth syndrome Xq28 TAZ X-linked Xq21.
With the new possibilities of configuration and calibres SBDS
offers a variety of solutions.
This contract is the largest volume of mortar rounds ever produced at SBDS, says Stephan Kocher, head of Saab Bofors Dynamics Switzerland.
SBDS is an industry leader in the design, development and production of mortar rounds, warheads, less-lethal applications and other energetic products.
NLT) have today signed a long-term cooperation agreement whereby SBDS will market and sell the IronFistTMand Cobra40TMless-lethal weapon systems, including their 38-mm and 40-mm munitions, on an exclusive basis in the European market.
SBDS is a fully-owned company of Sb, located in Thun, Switzerland and organized within Sb s Business area Dynamics.
NLT and SBDS will make a world-class team given both companies prominent positions in their markets with superior products.