Physical, neurological examinations (including SNCV and MNCV) and slit skin smears were repeated at 6 monthly intervals in all the patients reporting for follow up and as and when a patient presented with reaction episode.
Assessments using SNCV and MNCV were done in 365 patients, of which 336 (92%) showed abnormal nerve function of one or more parameters in the nerves tested.
Overall, of the 2920 sensory and motor nerves examined using SNCV and MNCV, 1532 (52%) and 1078 (37%) respectively showed impairment (Table 10).
The proportion of patients as well as nerves affected by SNCV was two-fold higher than MF and MNCV was six-fold higher than VMT proving NCV to be the more sensitive in detecting NFI.
The most commonly used and time-tested clinical tests to record nerve function impairment include graded MF and VMT both of which were used in this study, along with MNP, SNCV and MNCV measurements.
In terms of number of nerves, the proportion of sensory and motor nerves showing abnormal nerve function by SNCV andMNCV were two and four-fold higher than by MF and VMT respectively.
Consistent measurements of radial and ulnar SNCVs and CDPs have been described in anesthetized mallard ducks, and the CDP was shown to reflect accurately the integrity of the brachial plexus.
The radial and ulnar SNCVs were determined by dividing the stimulus to recording site distance by the CNAP latency.
For groups 1, 2, 3, and 5, radial and ulnar CNAPs, radial and ulnar SNCVs, and CDP amplitudes were recorded before treatment and then at 5, 30, and 60 minutes after injection.
Radial and ulnar CNAPs, radial and ulnar SNCVs, and CDP amplitudes were consistently recorded in all cases (groups 1, 2, 3, and 5) before and after treatment administration.
Preinjection values for radial and ulnar SNCVs were statistically similar to postinjection values.