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STAT3 |
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17 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) Hs. Chronically activated NF-kB and STAT3 are found in many forms of cancer and are associated with tumor progression, invasion, metastasis, and resistance to therapy. Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. |
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