Down regulation of HWP1 and SAP1 genes directly correlates with results observed in separate experiments of morphological transition and proteinase production, respectively.
Down regulation of HWP1 gene with respect to control cells was observed to be 65% whereas the ratio further increases to 85% for SAP1 gene.
1999); SAP1 (secreted aspartyl proteinase) known to cause tissue damage (Naglik et al.
Because all the main characteristic bands of SAP1 were overlapped with those of SAP2 and SAP3, it was difficult to ensure that SAP1 was the copolymer of SA and sodium l-(acryloyloxy) propan-2-yl phosphate by IR spectroscopy.
However, SWA of SAP1 and SAP3 were obviously affected by pH.
As a result, SWA of SAP1 showed a maximum at pH = 6.