| Acronym | Definition |
|---|
| SPA | Spanish (language) |
| SPA | Società Per Azioni (Italian: shared company) |
| SPA | Software Publishers Association (now SIIA) |
| SPA | Single Point of Access (AT&T) |
| SPA | Special Protocol Assessment |
| SPA | School of Public Affairs (American University, Washington, DC) |
| SPA | Saudi Press Agency |
| SPA | Special Protection Area |
| SPA | Secure Password Authentication |
| SPA | Sanus Per Aquam (Latin: health through water) |
| SPA | Société Protectrice des Animaux (French: Protective Company of Animals) |
| SPA | Stock Purchase Agreement |
| SPA | Sponsored Programs Administration |
| SPA | Share Purchase Agreement |
| SPA | Sociedade Portuguesa de Autores (Portugal) |
| SPA | Sociedade Portuguesa de Autores |
| SPA | Supreme People's Assembly (North Korea) |
| SPA | Scintillation Proximity Assay |
| SPA | Society for Public Administration |
| SPA | Simple Power Analysis |
| SPA | Single Photon Absorptiometry (bond density test, measures the wrist) |
| SPA | Single Pitch Award (rock climbing) |
| SPA | Standardized Performance Analysis (stock breeding) |
| SPA | Specially Protected Area (under Antarctic Treaty) |
| SPA | Social Policy Association (UK) |
| SPA | Sales and Purchase Agreement |
| SPA | Single Packet Authorization |
| SPA | Sperm Penetration Assay |
| SPA | Senior Policy Advisor |
| SPA | Serviço de Psicologia Aplicada (Portuguese: Department of Applied Psychology; Brazil) |
| SPA | Securities Purchase Agreement (legal) |
| SPA | Sindicato de Periodistas de Andalucía (Spanish: Union of Journalists of Andalusia; Spain) |
| SPA | Software Process Assessment |
| SPA | School of Planning and Architecture (India) |
| SPA | Special Power of Attorney |
| SPA | South Pole-Aitken (Basin) |
| SPA | Society for Personality Assessment |
| SPA | Single Parent Adoption |
| SPA | Self Propelled Artillery |
| SPA | Society for Pediatric Anesthesia |
| SPA | Seaplane Pilots Association |
| SPA | Systems Planning and Analysis, Inc. |
| SPA | Service Provider Access |
| SPA | Special Planning Area (planning and development) |
| SPA | single page application (web pages) |
| SPA | Software Piracy Association |
| SPA | Supporting Professionalism in Admissions (UK education) |
| SPA | Security Posture Assessment |
| SPA | Service Provision Assessment |
| SPA | Saint Paul Academy |
| SPA | Saab Parking Assistance (Saab) |
| SPA | Specialty Professional Association (education) |
| SPA | Small Project Assistance (USAID) |
| SPA | Sum-Product Algorithm |
| SPA | Socrates Plato Aristotle (mnemonic for ancient philosophers) |
| SPA | Sheep Pulmonary Adenomatosis |
| SPA | Surinaamse Partij van de Arbeid (Suriname Labor Party) |
| SPA | Socialist Party of Albania |
| SPA | Service Provider Application |
| SPA | Smart Pixel Array |
| SPA | State Program Approval |
| SPA | Sociological Practice Association |
| SPA | Special Prorate Agreement (airlines fares agreement) |
| SPA | Patriotic Movement of Sint Maarten (Netherlands Antilles) |
| SPA | Software Product Assurance |
| SPA | Systems & Process Assurance (PricewaterhouseCoopers, LLP) |
| SPA | Softball Players Association |
| SPA | Society of Professional Accountants |
| SPA | Sanum Per Aqua (Latin: Health Through Water) |
| SPA | Simplified Purchase Agreement |
| SPA | Single Point Accountability |
| SPA | Source Prescription Audit |
| SPA | System Performance Assessment |
| SPA | Salt Poor Albumin |
| SPA | Sanctuary Preservation Area |
| SPA | Society of Philatelic Americans |
| SPA | Single Project Assurances |
| SPA | Security Process Algebra |
| SPA | Special Purpose Aircraft |
| SPA | Strategic Planning Application |
| SPA | Student Progress and Achievement |
| SPA | Shared Port Adaptor (Cisco) |
| SPA | Saddlepoint Approximation |
| SPA | Special Post Allowance |
| SPA | Servo Power Amplifier |
| SPA | Sfonda una Porta Aperta |
| SPA | Special Programme on AIDS (now Global Programme on AIDS) |
| SPA | Summary Proceedings Act (New Zealand) |
| SPA | Summit Pathology Associates (Akron, OH) |
| SPA | Solar Panel Assembly |
| SPA | Sexiest Person Alive |
| SPA | Safe Plan of Action (UK) |
| SPA | School-Based Practical Assessment |
| SPA | Special Project Assignments |
| SPA | Saludis Per Aqua (Latin: Health Through Water) |
| SPA | Single Purpose Application |
| SPA | Safe Passages to Adulthood |
| SPA | Special Pricing Agreement |
| SPA | Submarine Patrol Area |
| SPA | Single Power Analysis (cryptographic attack) |
| SPA | Service Package Application |
| SPA | Single Point Administration |
| SPA | Software Product Assessment |
| SPA | Soft Physical Address |
| SPA | System Programmer Analyst |
| SPA | Sierra Pacific Tours |
| SPA | Solas Per Aqua (Latin: Health by Water) |
| SPA | Secure Platform Architecture (HP-Compaq) |
| SPA | Signal Processing Algorithms, Architectures, Arrangements and Applications (conference) |
| SPA | Protocol Address of the Sender |
| SPA | Special Purchase Allowance |
| SPA | Senior Police Advisor |
| SPA | Society for Personnel Administration |
| SPA | Students for Political Action (Ontario, Canada) |
| SPA | Spies Per Acre (online strategy gaming) |
| SPA | Specification Preparing Activity |
| SPA | Strike Planning Archive |
| SPA | Strategic Psychological Activities |
| SPA | Specific Poll Address (SS7) |
| SPA | Switched Parasitic Array |
| SPA | Strategic & Policy Assessment |
| SPA | Special Purpose Access |
| SPA | Suspended Plate Antenna |
| SPA | Social Progressive Alternative Party (Belgium) |
| SPA | Square Patch Antenna |
| SPA | Sprint Provided Access |
| SPA | SSCC POSIX APIs (NASA) |
| SPA | Standard Peak Area (gas chromatography) |
| SPA | Service Performance Assurance |
| SPA | Special Project Authorization |
| SPA | Small Payload Attachment |
| SPA | Sensor Performance Analysis |
| SPA | Spaces Per Aircraft |
| SPA | Sampling Probe Algorithm |
| SPA | Scalable Processing Architecture |
| SPA | Strategic Posture Analysis |
| SPA | Subsystem Performance Assessment |
| SPA | Security Plan Assistant |
| SPA | Shekijah Preparation Assembly (interdenominational church in Lynchburg, VA) |
| SPA | Successive Parallel Arbitrated (decision feedback mechanism) |
| SPA | SCSI Peripheral Adapter |
| SPA | Stochastic Prosesses and their Applications (peer reviewed journal) |
| SPA | Standard Plate Agar |
| SPA | Synthetic Parallel Application |
| SPA | SOSUS Probability Area |
| SPA | Scanner Power Assembly |
| SPA | Selectable Power Adapter |
| SPA | Skill Performance Aid |
| SPA | Single Person Accountability |
| SPA | Surface Preprocessing Assembly |
| SPA | Syndicated Program Analysis |
| SPA | Signaling Point Adjunct |
| SPA | Shanghai Prison Administration |
| SPA | Sectored Phased Array Antenna |
| SPA | Signaling Point Adapter |
| SPA | Single Piece Anode |
| SPA | Seafood Products Association (Seattle, WA) |
| SPA | Special Purpose Adapter |