Potential protective properties of flax lignan secoisolariciresinol
As results, 10 known compounds were firstly isolated from this plant, and elucidated as 7-(3-ethoxy-5-methoxyphenyl) propane-7,8,9-triol (1) , secoisolariciresinol
(2), (+)-pinoresinol (3), syringaresinol (4), and eugenyl-O-b-D-glucopyranoside (5) , benzyl-O-b-D-glucopyranoside (6) , p-hydroxy-benzaldehyde (7) , vanillin (8) , syringaldehyde (9) and 3-hydroxy-l-(4-hydroxy-3, 5-dimethoxyphenyl)-1-propanone (10) (Fig.
Suppression of phosphoenolpyruvate carboxykinase gene expression by secoisolariciresinol
diglucoside (SDG), a new antidiabetic agent.
Prasad K: Oxidative stress as a mechanism of diabetes in diabetic BB prone rats: Effect of secoisolariciresinol
AlaLife flax lignan is a standardized flaxseed extract with high quality lignans, particularly secoisolariciresinol
Flaxseed is one of the richest sources of a plant lignan called secoisolariciresinol
Washington State University (Pullman, WA) has patented a secoisolanciresinol dehydrogenase protein isolated from Forsythia intermedia, together with cDNAs encoding secoisolariciresinol
dehydrogenase from this species.
Flaxseed contains secoisolariciresinol
diglycoside (SDG), a phytoestrogen (PE) proposed to have both estrogenic and anti-estrogenic properties.
The major lignans identified in humans are now termed enterolactone and enterodiol, and they are described as resulting from bacterial transformation in the large bowel of matairesinol and secoisolariciresinol
, respectively (25-27).
Flaxseed is also rich in total dietary fiber (28 percent) and a lignan, secoisolariciresinol
diglucoside (SDG), which also offers powerful nutraceutical benefits.
Antidiabetic effect of secoisolariciresinol
diglucoside in streptozotocin-induced diabetic rats.
Flax meal, which is devoid of oil, contains the lignan secoisolariciresinol