| Acronym | Definition |
|---|
| SPR | Salient Pole Rotor |
| SPR | Salvage Point Recording |
| SPR | Sam Park Revue (stage comedy troupe) |
| SPR | San Pedro, Belize - San Pedro (Airport Code) |
| SPR | Sandia Pulse Reactor |
| SPR | Sapper |
| SPR | Saving Private Ryan (movie) |
| SPR | Schools and Programmes Register (Ghana) |
| SPR | Second Parent Rider (life insurance) |
| SPR | Seconds Per Rotation |
| SPR | Secretarial Performance/Program Review |
| SPR | Secure Packet Radio |
| SPR | Secure-Path Routing |
| SPR | Selected Place of Residence |
| SPR | Semiconductor Process Representation |
| SPR | Sepiapterin Reductase |
| SPR | Sequential Probabilistic Resource (resource reservation strategy) |
| SPR | SHARP Proactive Routing Protocol |
| SPR | Shortest Path Routing |
| SPR | Signal Processor |
| SPR | Single Package Radio (Skyworks) |
| SPR | Single Point of Reference |
| SPR | Single Point Refueling |
| SPR | Site Plan Review |
| SPR | Small Particle Reagent |
| SPR | Smart Plant Review (Intergraph) |
| SPR | Sociedade Paulista de Radiologia e Diagnóstico por Imagem |
| SPR | Society for Pediatric Radiology |
| SPR | Society for Psychical Research |
| SPR | Society for Psychophysiological Research |
| SPR | Software Portability Review |
| SPR | Software Problem Report |
| SPR | Software Product Report |
| SPR | Software Productivity Research |
| SPR | South Pacific Region (USACE) |
| SPR | Space Power Reactor |
| SPR | Sparse Point Representation |
| SPR | Spawning Potential Ratio (fisheries) |
| SPR | Special Processing Request |
| SPR | Special Program Requirement/Review |
| SPR | Special Purpose Register |
| SPR | Special Purpose Rifle |
| SPR | Special Requisition |
| SpR | Specialist Registrar (UK doctor who supports a consultant) |
| SPR | Specific Physiological Response (polygraphy) |
| SPR | Sponsor's Program Review |
| SPR | State Performance Reports |
| SPR | Statement of Procedural Rules (IRB) |
| SPR | Stop Prisoner Rape |
| SPR | Stowage Problem Report |
| SPR | Strategic Petroleum Reserve |
| SPR | Strategic Planning Review |
| SPR | Student-Produced Response (SAT testing) |
| SPR | Subpixel Rendering |
| SPR | Suomen Punainen Risti |
| SPR | Surface Plasmon Resonance |
| SPR | Swiss Poster Research |
| SPR | Synchronous Persistent Repetition |
| SPR | System Performance Report |
| SPR | System Performance Requirement(s) |
| SPR | System Post-deployment Review |
| SPR | System Problem Report |
| SPR | System Program Review |
| SPR | Systems Programming Request |
| SPR | Screen Program |
| SPR | Serial Peripheral Rate |
| SPR | Shared Protection Ring |
| SPR | Standard Cell Place and Route |
| SPR | Standard Pixel Run |
| SPR | Systeme De Production Renault |
| spr | Schipper (Dutch) |
| spr | Spring |
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Secure-Path Routing