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The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial, recently completed, aimed to define which subsequent treatment strategies, in what order or sequence, and in what combination(s) were both acceptable to patients and provide the best clinical results with the least side effects. John Rush of the University of Texas Southwestern Medical Center at Dallas, director of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial. The Sequenced Treatment Alternatives to Relieve Depression study, or STAR*D, funded by the National Institute of Mental Health (NIMH) was the nation's largest study of treatment-resistant depression. |
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