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Mortality was originally estimated to be nearly 80%, but since the introduction of the skeletal muscle relaxant dantrolene (the only specific drug indicated for the treatment of malignant hyperthermia) in 1975, mortality has been reported to be less than 10%. Part 4, "Disorders of Movement," is the shortest section and includes a chapter on Parkinson's disease, a chapter on antiepileptic drugs, and a three-page chapter entitled "Spasticity and Skeletal Muscle Relaxants. Atracurium besylate injection is an intermediate-duration skeletal muscle relaxant for intravenous administration which is used as an adjunct to general anesthesia during surgery or mechanical ventilation," Moldin said. |
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