| Acronym | Definition |
|---|
| SFR | Swiss Franc (national currency) |
| SFR | Single Family Residence (real estate) |
| SFR | Single Family Residence |
| SFR | Société Française du Radiotéléphone (French cellular provider) |
| SFR | Split Frame Rendering (computer graphics processing) |
| SFR | Special Function Register (Intel 8051 Microcontroller) |
| SFR | Substitute For Return |
| SFR | Star Formation Rate |
| SFR | Société Française de Radiologie |
| SFR | School of Forest Resources (various locations) |
| SFR | Spatial Frequency Response |
| SFR | Star Forming Region |
| SFR | Société Française de Rhumatologie |
| SFR | Sodium Fast Reactor |
| SFR | System Functional Review |
| SFR | Special Forces Regiment |
| SFR | Starfsmannafélag Ríkisstofnana (Icelandic: Association of Government Personnel) |
| SFR | Strange Famous Records |
| SFR | Swiss Federal Railway |
| SFR | Small-Farm Reservoir |
| SFR | Slovak Federal Republic |
| SFR | Santa Fe Re-Creations |
| SFR | Special Flight Rules |
| SFR | Spin-Flip Raman |
| SFR | Stable Free Radical |
| SFR | Shinden Fudo Ryu (Martial Arts; Bujinkan) |
| SFR | South Florida Raves |
| SFR | Step Frequency Radar |
| SFR | Synchronous Fixed Repetition |
| SFR | Salary Factor Report |
| SFR | Spectral FEG Resequencing |
| SFR | Safety of Flight Requirements |
| SFR | Shanghai-Fanuc Robotics, Ltd. |
| SFR | Special Friends Records |
| SFR | Status of Forces Report |
| SFR | Semiannual Force Revision |
| SFR | Starfleet Republic headquarters (Star Trek role playing game) |
| SFR | Shift Finger Rail |
| SFR | Significant Finding Report |
| SFR | System-Fault-Risk (computer systems) |
| SFR | Ship's Hazardous Material List Feedback Report |
| SFR | South Flintshire Radio |
| SFR | South Farms Review (publication, University of Illinois at Urbana-Champaign) |
| SFR | San Francisco Reporting Service (court reporting) |
| SFR | Software Functional Requirement |
| SFR | Scottish Forest Rally School |
| SFR | Shunt Field Resistance |
| SFR | Sex Factor Regulation |
| SFR | Software Fault Report |
| SFR | Sarah Fisher Racing (racing team) |
| SFR | Statistical First Release (Department for Education; UK) |
| SFR | School Fund Raiser (various locations) |
| SFR | Structure Function Relationship (biology) |
| SFR | Student to Faculty Ratio (educational statistic) |
| SFR | Ship from Remote Location (various companies) |
| SFR | Strathclyde Fire & Rescue (UK) |
| SFR | Santa Fe Reporter (newspaper; Santa Fe, NM) |