| Acronym | Definition |
|---|
| SRE | Secretaría de Relaciones Exteriores (México) |
| SRE | Society of Reliability Engineers (Canada) |
| SRE | Snow Removal Equipment (US FAA) |
| SRe | Seychelles Rupee (national currency) |
| SRE | Standard for Robot Exclusion (web indexing crawlers) |
| SRE | Site Reliability Engineer |
| SRE | Solar Realms Elite (online game) |
| SRE | Software Risk Evaluation |
| SRE | Software Reliability Estimation |
| SRE | Sucre, Bolivia - Sucre (Airport Code) |
| SRE | Schema Runtime Environment (computing) |
| SRE | System Requirements Engineering |
| SRE | SQUID Readout Electronics |
| SRE | Scottish Rootes Enthusiasts |
| SRE | Sources Renouvelables d'Energie (French: Renewable Sources of Energy) |
| SRE | Single Round Effectiveness |
| SRE | Smart Renewable Energies |
| SRE | Search Radar Element |
| SRE | Settlement Reporting Entity |
| SRE | Society for Radiological Engineering |
| SRE | Shift Register Encode |
| SRE | Self-Recovering Equalization |
| SRE | Slow Response Engine |
| SRE | Signaling Reduction Efficiency |
| SRE | Service Régional de l'Equipement (French: Regional Service of Equipment) |
| SRE | Slit Rolled Edge (stainless steel metal surface finish) |
| SRE | Speech Recognition Engine |
| SRE | Senior Resident Engineer (various companies) |
| SRE | Serum Response Element (biochemistry) |
| SRE | Software Re-Engineering |
| SRE | Software Reliability Engineering |
| SRE | Size Reduction Equipment |
| SRE | Services and Routing Engine (Gateway) |
| SRE | Surveillance Radar Equipment |
| SRE | Sancta Romana Ecclesia (Latin: Holy Roman Church, epigraphy) |
| SRE | Self Routing (Switch) Element |
| SRE | Symposium on Requirements Engineering (IEEE International Symposium) |
| SRE | Skeletal Related Event |
| SRE | Signal Reference Earth (electric installations) |
| SRE | Sex and Relationship Education |
| SRE | Standard Renewable Energy (various locations) |