| Acronym | Definition |
|---|
| SMG | Sub-Machine Gun |
| SMG | Sub Machine Gun (gaming, Halo 2) |
| SMG | Super Mario Galaxy (game) |
| SMG | Sarah Michelle Gellar |
| SMG | Sequential Manual Gearbox (BMW) |
| SMG | Social Media Group (Canada) |
| SMG | School of Management (School of Management at Boston University) |
| SMG | Stock Market Game |
| SMG | Senior Management Group (JWID) |
| SMG | Syndicat de La Médecine Générale (French: Union of General Medicine; est. 1975) |
| SMG | Scandinavian Music Group (Finnish band) |
| SMG | Special Mobile Group (ITU 3G telecom standards development body) |
| SMG | Spaceflight Meteorology Group |
| SMG | Strategic Marketing Group (Lake Tahoe, CA) |
| SMG | Sister Machine Gun (band) |
| SMG | Speed Made Good |
| SMG | Solutions Marketing Group |
| SMG | Strategic Management Group, Inc. |
| SMG | Sales and Marketing Group (Intel) |
| SMG | Sonic Mega Collection (video game) |
| SMG | Suchtgiftverordnung (Austrian narcotics law) |
| SMG | Silenced Machine Gun (gaming) |
| SMG | Shoreline Management Guidelines |
| SMG | Statistical Multiplexing Gain |
| SMG | Survivable Media Gateway (Siemens) |
| SMG | Services Management Group |
| SMG | Supermastergroup |
| SMG | Standard Mail Guard |
| SMG | Secure Mail Gateway |
| SMG | Service Management Gateway |
| SMG | Semi-Manual Gearbox |
| SMG | Super MechaGodzilla (fan fiction) |
| SMG | Somali Manifesto Group (political party) |
| SMG | Secure Mail Guard |
| SMG | Société Métallurgique de Gerzat (French: Metallurgical Society of Gerzat; France) |
| SMG | Symposium Mines Guinée (French: Guinea Mining Symposium) |
| SMG | Sliding Mode Guidance |
| SMG | Simulation Model Generator |
| SMG | Shelter Management Guide |
| SMG | Software Message Generator |
| SMG | Sportplatz Maschinenbau GmbH (German: Sports Ground Engineering Ltd.) |
| SMG | Societe Méridionale de Granulats (French: Company of Southern Aggregates) |
| SMG | Studio Movie Grill (various locations) |
| SMG | Staff Major General (various armed forces) |
| SMG | St. Maria Goretti (various locations) |
| SMG | Shanghai Municipal Government (Shanghai, China) |
| SMG | Sentara Medical Group (Virginia) |
| SMG | Sisselman Medical Group, PC |