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ERs, like the rest of the steroid hormone receptor family, have a hormone-binding domain and a DNA-binding domain that is dominated by zinc-finger motifs. I was distressed to read that SCIENCE NEWS thinks there are no steroid hormone receptors in insects ("Ancient estrogen," SN: 8/11/01, p. These client proteins represent a Who's Who list of the important kinase targets in oncology as well as steroid hormone receptors. |
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