| Acronym | Definition |
|---|
| spr | Spring |
| SPR | Strategic Petroleum Reserve |
| SPR | Surface Plasmon Resonance |
| SPR | Saving Private Ryan (movie) |
| SpR | Specialist Registrar (UK doctor who supports a consultant) |
| SPR | Society for Psychical Research |
| SPR | Suomen Punainen Risti |
| SPR | Site Plan Review |
| SPR | Sapper |
| SPR | Software Productivity Research |
| SPR | Society for Pediatric Radiology |
| spr | Schipper (Dutch) |
| SPR | Swiss Poster Research |
| SPR | Software Problem Report |
| SPR | Stop Prisoner Rape |
| SPR | Society for Psychophysiological Research |
| SPR | Signal Processor |
| SPR | Society for Psychotherapy Research (behavioral science group) |
| SPR | Special Purpose Rifle |
| SPR | Sepiapterin Reductase |
| SPR | Spawning Potential Ratio (fisheries) |
| SPR | Special Purpose Register |
| SPR | Statistical Techniques in Pattern Recognition (workshop) |
| SPR | Shortest Path Routing |
| SPR | Special Project Report |
| SPR | Small Particle Reagent |
| SPR | System Problem Report |
| SPR | Self Piercing Rivet |
| SPR | Sociedade Paulista de Radiologia e Diagnóstico por Imagem |
| SPR | Subpixel Rendering |
| SPR | South Pacific Region (USACE) |
| SPR | San Pedro, Belize - San Pedro (Airport Code) |
| SPR | System Performance Report |
| SPR | Single Point Refueling |
| SPR | Student-Produced Response (SAT testing) |
| SPR | Sandia Pulse Reactor |
| SPR | Semiconductor Process Representation |
| SPR | Sparse Point Representation |
| SPR | Smart Plant Review (Intergraph) |
| SPR | Single Package Radio (Skyworks) |
| SPR | Staatspunkrott (German band) |
| SPR | Syndrome de Pierre Robin (French: Pierre Robin Syndrome) |
| SPR | Sudden Pressure Relay (ABB Group; gas pressure measurement device) |
| SPR | Strategic Planning Review |
| SPR | Special Problem Report (US FEMA) |
| SPR | State Performance Reports |
| SPR | Special Processing Request |
| SPR | Selected Place of Residence |
| SPR | Service Prévention des Risques (French: Service Risk Prevention) |
| SPR | Statement of Procedural Rules (IRB) |
| SPR | System Program Review |
| SPR | Special Production Racing (motorcycle model) |
| SPR | Sam Park Revue (stage comedy troupe) |
| SPR | SHARP Proactive Routing Protocol |
| SPR | Single Point of Reference |
| SPR | Seconds Per Rotation |
| SPR | Space Power Reactor |
| SPR | Secure-Path Routing |
| SPR | Software Product Report |
| SPR | Service Performance Review |
| SPR | Sponsor's Program Review |
| SPR | Special Requisition |
| SPR | Specific Physiological Response (polygraphy) |
| SPR | Second Parent Rider (life insurance) |
| SPR | System Post-deployment Review |
| SPR | Salient Pole Rotor |
| SPR | Salvage Point Recording |
| SPR | Sequential Probabilistic Resource (resource reservation strategy) |
| SPR | Secretarial Performance/Program Review |
| SPR | Secure Packet Radio |
| SPR | Stowage Problem Report |
| SPR | Sistema de Proteção Contra Riscos Financeiros (Brasil) |
| SPR | Service des Programmes et du Réseau (French: Programs and Services Network) |
| SPR | Schools and Programmes Register (Ghana) |
| SPR | Synchronous Persistent Repetition |
| SPR | Software Portability Review |
| SPR | Special Program Requirement/Review |
| SPR | Systems Programming Request |
| SPR | System Performance Requirement(s) |
| SPR | Short Prose Reader (anthology) |
| SPR | Special Pinch Runner (little league baseball) |
| SPR | Strategic Public Relations (various organizations) |
| SPR | Shortest Possible Route |
| SPR | Small Pressurized Rover |
| SPR | Southern Poetry Review (est. 1958) |
| SPR | Service Provider Reseller |
| SPR | Spill Prevention and Response (various locations) |
| SPR | School Psychology Review (National Association of School Psychologists) |
| SPR | Self Paced Reading (psycholinguistics) |
| SPR | Standard Progress Report (various organizations) |