| Acronym | Definition |
|---|
| SCI | Science |
| SCI | Sensitive Compartmented Information (US government classified information) |
| SCI | Safari Club International |
| SCI | Service Corporation International |
| SCI | Spinal Cord Injury |
| SCI | Science Citation Index (Institute for Scientific Information) |
| SCI | String Cheese Incident (band) |
| SCI | Shipping Corporation of India |
| SCI | Societe Civile Immobiliere (French legal status for firms) |
| SCI | Service Civil International |
| SCI | Sister Cities International |
| SCI | Systemics, Cybernetics and Informatics |
| SCI | State Correctional Institution (various states) |
| SCI | Steel Construction Institute |
| SCI | Shanghai Composite Index |
| SCI | Scalable Coherent Interface |
| SCI | Santa Catalina Island (California, USA) |
| SCI | Serial Communications Interface |
| SCI | Solar Cookers International |
| SCI | San Clemente Island (California) |
| SCI | Supply Chain Integration |
| SCI | Sales Curve Interactive |
| SCI | Sport Club Internacional |
| SCI | Systems Concepts and Integration (NATO) |
| SCI | Statement of Corporate Intent (operations agreement) |
| SCI | Special Compartmented Information |
| SCI | Scalable Coherent Interconnect |
| SCI | Software Configuration Item |
| SCI | Sierra Creative Interpreter |
| SCI | Structured Credit Investor (UK) |
| SCI | Sensitive Compartmented Intelligence |
| SCI | Swedish Corrosion Institute |
| SCI | Special Crash Investigation |
| SCI | Share Capital Increase (stock value) |
| SCI | Stream Condition Index (ecology) |
| SCI | Software Configuration Index |
| SCI | SciFi Communications International |
| SCI | Sequential Circuits Inc. (California) |
| SCI | Steven Counts, Inc. (Summerfield, FL) |
| SCI | Southern Cross International |
| SCI | Sputtering Components, Inc. (various locations) |
| SCI | Sensibilité aux Conditions Initiales (French: sensitivity to initial conditions) |
| SCI | Superior Contribution Increase (FAA Core Compensation System) |
| SCI | Software Configuration Identification |
| SCI | Subscriber Controlled Input (Siemens) |
| SCI | Speaking Circles International |
| SCI | Sharing with Complete Information |
| SCI | Significant Cost Impact |
| SCI | Security Clearance Interim |
| SCI | Single-Column Inch |
| SCI | Safety Critical Item |
| SCI | Surrender Cost Index (insurance) |
| SCI | Service Contractors, Inc. |
| SCI | Supplemental Card Indicator |
| SCI | Spore Coloration Index (geochemistry) |
| SCI | Ship Controlled Intercept |
| SCI | Stratospheric Circulation Model |
| SCI | Strategic Council for Innovation |
| SCI | Support Collectors, Inc. |
| SCI | Standard Components Inc. (Sterling Heights, MI) |
| SCI | Sea Containers Inc. |
| SCI | Switch Communication Interface (AT&T) |
| SCI | Ministerial Committee on Science Policy (UK) |
| SCI | Space Craft Incorporated |
| SCI | Specification Change Index |
| SCI | Source Code Identifier (military intelligence) |
| SCI | Special Control Item |
| SCI | Super Computer Incorporated |
| SCI | Stratus Computer Incorporated |
| SCI | Support Coordinating Installation |
| SCI | Subscriber Circuit Interface |
| SCI | Special Circumstance Instruction (legal) |
| SCI | Society of Chemical Industry (also seen as SOCI; UK) |
| SCI | System Call Interface (computer programming) |
| SCI | St. Catherines Island (Georgia) |
| SCI | Società Chimica Italiana (Italian: Italian Chemical Society) |
| SCI | Studies in Computational Intelligence (journal; Springer) |
| SCI | Supply Chain Initiative |
| SCI | Shopping Cart Interface (software) |
| SCI | Simmons & Company International (Houston, TX) |
| SCI | Strategic Consulting International (Tulsa, OK) |
| SCI | Statement of Community Invovlement (UK) |
| SCI | Sinai Consulting Inc (Granger, IN) |
| SCI | Social Cohesion and Identity (Human Sciences Research Council; South Africa) |
| SCI | SAAB (Svenska Aeroplan Aktiebolaget) Club Italia (Italian car club) |