| Acronym | Definition |
|---|
| SMI | Structure of Management Information |
| SMI | Serious Mental Illness |
| SMI | Storage Management Initiative (HP) |
| SMI | Speedway Motorsports, Inc. |
| SMI | Sun Microsystems, Inc. |
| SMI | Supplementary Medical Insurance |
| SMI | Scientology Missions International |
| SMI | Shape Modeling International (International Conference) |
| SMI | Standard Multilayer Software Image (Cisco) |
| SMI | Severely Mentally Ill |
| SMI | Système de Management Intégré (French: Integrated Management System) |
| SMI | Supplemental Medical Insurance (US Medicare Part B) |
| SMI | Supplier Managed Inventory (supply chain management) |
| SMI | System Management Interrupts |
| SMI | System Monitoring Interface |
| SMI | Stanford Medical Informatics |
| SMI | Society for Molecular Imaging (Kerrville, TX) |
| SMI | Safe Motherhood Initiative |
| SMI | Surface Minimum d'Installation (French: Minimum Installation Area; farming) |
| SMI | Severely Mentally Impaired |
| SMI | Secret of Monkey Island |
| SMI | Sample Matrix Inversion |
| SMI | Spring Manufacturers Institute |
| SMI | School Meals Initiative for Healthy Children (USDA) |
| SMI | Serial Management Interface |
| SMI | Structure Model Index (bone mass) |
| SMI | St Michael's Institution (Malaysia) |
| SMI | Shared Memory Interface |
| SMI | Sisters of Mary Immaculate (religious order) |
| SMI | Specialty Manufacturing Inc (San Diego, CA) |
| SMI | Security Management Infrastructure |
| SMI | Soldier/Machine Interface |
| SMI | Service Médical International (French: International Medical Service; est. 1983) |
| SMI | Senior Military Instructor (Army ROTC) |
| SMI | Structured Materials Industries, Inc. |
| SMI | Swiss Meteorological Institute |
| SMI | Specialty Motions, Inc (Corona, CA) |
| SMI | Samos Island, Greece (Airport Code) |
| SMI | Small Medium Industry |
| SMI | Soil Moisture Index |
| SMI | Scientific Monitoring, Inc. (Scottsdale, AZ) |
| SMI | Strategic Modernization Initiative |
| SMI | Strategic Management Institute (Stockholm, Sweden) |
| SMI | Supply Management Inspection |
| SMI | Security Management Information |
| SMI | Smart Metering Infrastructure (Australia) |
| SMI | Southern Military Institute |
| SMI | Silent Myocardial Infarction |
| SMI | Systems and Methods Inc (Georgia) |
| SMI | Smart Money Index |
| SMI | Statistical Mechanical Informatics |
| SMI | Sean Murphy Induction (Huntington Beach, CA manufacturer of custom built carburetors for automotive applications) |
| SMI | Subsystem Multiplicity Indicator (SS7 SCCP) |
| SMI | Senior Marine Instructor (USMC JROTC) |
| SMI | Service Management Interface |
| SMI | Sergeant Major Instructor |
| SMI | Saturday Morning Inspection |
| SMI | Sudden Money Institute |
| SMI | Sphincter Mechanism Incompetence |
| SMI | Solutions de Marquage Industriel (French: Industrial Marking Solutions) |
| SMI | Service Médical Interentreprises (French: Business to Business Medical Service) |
| SMI | Sperry Marine Inc. |
| SMI | Saint Michael's Institute (New York, NY) |
| SMI | Structured Management Information |
| SMI | Strings Music Import (France) |
| SMI | Structural Mode Interaction |
| SMI | Société Mutualiste Interprofessionnelle (French: Mutual Interprofessional Company) |
| SMI | Starch Medical Inc (San Jose, CA manufacturer of surgical hemostasis products) |
| SMI | Simple Matrix Inversion |
| SMI | Secrétaires de Mairie Instituteurs (French: Town Clerk Teachers) |
| SMI | Sports Management International LLC |
| SMI | Sending Module ID |
| SMI | Sample Matrix Inverter |
| SMI | Sur-Mesure Industriel (French: On-Industrial Measurement; consulting firm; est. 1991) |
| SMI | Side Mount Intercooler (automotive turbo systems) |
| SMI | Saint Matthew Island (Alaska) |
| SMI | Surface Measuring Instrument |
| SMI | Société Méditerranéenne d'Informatique (French: Mediterranean Computer Company; est. 1983) |
| SMI | Self-Mounting floppy disk Image (Mac OS File Extension) |
| SMI | Ship Modification Instruction |
| SMI | Ship Manpower Information |
| SMI | Sherwood Manufacturing, Inc. (Longmont, CO) |
| SMI | Standard Multilayer Image (Cisco) |
| SMI | Swiss Market Index (trademark of SWX Swiss Exchange) |
| SMI | Student Medical Insurance |
| SMI | Sports Media, Inc. (est. 1991) |
| SMI | Sustainable Minerals Institute (Brisbane, Australia) |
| SMI | Sonitus Medical, Inc. (San Mateo, CA) |
| SMI | Slow-Moving Inventory |
| SMI | Solutions pour Maisons Intelligentes (French: Solutions for Intelligent Homes) |
| SMI | Sales & Marketing Institute |
| SMI | Symbolic Music Information (computer programming) |
| SMI | Société Moderne d'Isolation (French: Modern Insulation Company; est. 1985) |