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SMN |
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In 1995, two candidate genes were identified-the survival motor neuron (SMN) gene, and the neuronal inhibitor of apoptosis protein (NAIP) gene (1). Spinal Muscular Atrophy (SMA) is a common inherited and fatal neuromuscular disease caused by deletions and/or mutations that lead to altered concentrations of proteins encoded by the survival motor neuron genes SMN1 and SMN2. SMA is a genetic disorder that causes a chronic deficiency in the production of the Survival Motor Neuron ( |
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