| Acronym | Definition |
|---|
| SMO | Server Management Objects |
| SMO | Social Media Optimization |
| SMO | SQL Management Objects |
| SMO | Santa Monica Municipal Airport |
| SMO | Sabhal Mòr Ostaig (Scotland Gaelic college) |
| SMO | Site Management Organization |
| SMO | Senior Medical Officer |
| SMO | Service Message Object |
| SMO | Sequential Minimal Optimization |
| SMO | Social Marketing Optimization |
| SMO | Soil Moisture |
| SMO | Stichting Maatschappij en Onderneming (Dutch) |
| SMO | Santísimo (Spanish) |
| SMO | Social Movement Organization |
| SMO | Serious Mode On |
| SMO | Systems Management Office |
| SMO | Security Management Office |
| SMO | Southern Maryland Oil |
| SMO | SQL Management Object |
| SMO | Sample Management Office |
| SMO | System Management Office (US government agencies) |
| SMO | Support to Military Operations |
| SMO | Sociedad Mexicana de Ortopedia |
| SMO | Steunpunt Minderheden Overijssel (Dutch) |
| SMO | Survey and Mapping Office (Hong Kong) |
| SMO | Service Management Organization |
| SMO | Stepmania Online (gaming) |
| SMO | Singing Men of Ohio (Ohio University) |
| SMO | Second Medical Opinion |
| SMO | Service de Maîtrise d'Ouvrage (French: Department of Control of Work) |
| SMO | Single Market Observatory (EU) |
| SMO | Standing Medical Orders (EMS) |
| SMO | Supramalleolar Orthoses |
| SMO | Surveillance Medical Officer |
| SMO | Strategic Management and Organization |
| SMO | Shoujo Manga Outline |
| SMO | Support for Military Operations |
| SMO | Système Modulaire Optionnel (French: Optional Modular System; health insurance) |
| SMO | Simdesigner Motion |
| SMO | Sheet Metal Optimizer (software) |
| SMO | SMC Gold Ltd (stock symbol) |
| SMO | System Management Overview (OSI) |
| SMO | Sales Momentum (model) |
| SMO | State Machine Object |
| SMO | Sewing Machine Operator |
| SMO | Senior Military Officer (DPKO) |
| SMO | Singapore Maths Olympiad (Singapore) |
| SMO | Samoa Observatory (Cape Matatula, American Samoa) |
| SMO | Stores Management Overlay |
| SMO | Strategic Mobility Office (USMC term: MEF level and above mobility planners) |
| SMO | Seattle Metal Online |
| SMO | Supreme Maintenance Organization |
| SMO | Supply Management Officer |
| SMO | Software Measurement Ontology |
| SMO | Senior Military Observer |
| SMO | Single Molecule Optics |
| SMO | Small Mobile Office |
| SMO | Strong Motion Observation |
| SMO | Special Mission Optional Modification |
| SMO | Seattle Mandolin Orchestra |
| SMO | System and Market Operator |
| SMO | Stationing Management Office |
| SMO | Special Management Office |
| SMO | Saipan Mayor's Office |
| SMO | Site Maintenance Organization |
| SMO | Study Management Organization |
| SMO | Surplus Material Order (US DoD) |
| SMO | Sponsoring Member Organization |
| SMO | Stable Master Oscillator |
| SMO | Supply Management Office |
| SMO | Sociedad Mexicana de Oftamologia |
| SMO | Stratégie et Management des Organisations (French: Strategy and Organization Management) |
| SMO | Supervising Medical Officer |
| SMO | Shiny Metal Object |
| SMO | Surplus Move Order |
| SMO | Sales and Marketing Organization |
| SMO | Symptomatic Medication Overuse |