| Acronym | Definition |
|---|
| SPMS | Secondary Progressive Multiple Sclerosis |
| SPMS | School of Physical and Mathematical Sciences |
| SPMS | Student Progress Monitoring System |
| SPMS | Special Purpose Monitoring Stations |
| SPMS | Single Particle Mass Spectrometer |
| SPMS | Safety Performance Measurement System (US DOE) |
| SPMS | Strategic Planning and Management System |
| SPMS | Specialist Provider Medical Services (UK) |
| SPMS | Seri Paduka Mahkota Selangor (award) |
| SPMS | Scientific Program Management System |
| SPMS | South Pasadena Middle School (Pasadena, CA) |
| SPMS | Sparrows Point Middle School (Baltimore, Maryland) |
| SPMS | Strategic Performance Measurement System |
| SPMS | Switzerland Point Middle School (Fruit Cove, FL) |
| SPMS | Software Project Management System |
| SPMS | Software Process Management System |
| SPMS | Standard Personnel Management System (US Navy medicine) |
| SPMS | Severna Park Middle School (Maryland) |
| SPMS | South Park Middle School |
| SPMS | Stichting Pensioenfonds Medische Specialisten (Dutch: Pension for medicial specialist/consultants) |
| SPMS | South Preston Middle School (West Virginia) |
| SPMS | Standing Panel on Mobilizing Science |
| SPMS | South Paulding Middle School (Georgia) |
| SPMS | Supplier Performance Measurement System |
| SPMS | Special Purpose Manipulator System (NASA) |
| SPMS | Switch Performance Monitoring System |
| SPMS | Sea Pines Montessori School (Hilton Head Island, SC) |
| SPMS | Spare Parts Management System |
| SPMS | Structures Properties and Modelling of Solids |
| SPMS | SurPac Mining Software |
| SPMS | Society for Marketing Professional Services |
| SPMS | Supervisory Personnel Management Specialist |
| SPMS | Smart Power Measuring Sensor |
| SPMS | South Plainfield Middle School (South Plainfield, NJ) |
| SPMS | Storage Products Management System |
| SPMS | Safety Performance Management System (Australia) |
| SPMS | Service Provider Management System |
| SPMS | Specialty Performance Measurement System |
| SPMS | Swedish Project Management Society |
| SPMS | School of Postgraduate Medical Studies |
| SPMS | Special Programs Management Section |
| SPMS | Short Pump Middle School (Glen Allen, VA) |
| SPMS | Software Process and Management System |
| SPMS | Software Project Management Strategies |
| SPMS | Starship Personnel Management System |
| SPMS | Software Platform Management Services (IBM) |
| SPMS | Spatial Process Modelling System |
| SPMS | Syarikat Perniagaan Malar Setia |
| SPMS | Summer Physical Mathematical School |
| SPMS | Solar Particle Monitoring System |
| SPMS | Standard Personnel Manpower System |
| SPMS | Site Pavement Management Software |
| SPMS | Specialty Performance Management System |
| SPMS | Sustainable Performance Management System |
| SPMS | Simple Project Management System |
| SPMS | Service Point Management System |
| SPMS | Suppression Pool Makeup System |
| SPMS | Scaled Propagation Measurement System |
| SPMS | Sigma Property Management Services |
| SPMS | Special Planetary Militia Services |
| SPMS | State Permitted Mine Site |
| SPMS | Syrius PM Services, Inc. |
| SPMS | System Program Management Survey |
| SPMS | System Performance Management System |
| SPMS | Single Phase Melee System |