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Similarly, the expression of 18 cytokine genes (IL-7, IL-10, TNFAIP8, SPP2, TNFAIP3, IFNB, CCL19, TNFAIP8L1, IL-16, CNTF, CXCL13, TNFAIP8L3, TNFSF13B, IL-34, TGFB1, TNFAIP2, CCL3, and ADIPOQ) and 39 cytokine receptor genes (CXCR7, CSF2RA, IL-1RL1, I-L1R2, IL-17RA, IFNAR1, IL-18RAP, IL-31RA, IL-9R, IL-18R1, IL-20RB, IL-21R, IL-2RG, IL-20RA, IL-4I1, LILRB1, TLR1, IL-17REL, LILRB5, TGFBR1, TLR6, TNFRSF13B, XCR1, TLR7, TNFRSF13C, TLR15 etc.
Mutations in either TGFBR1 or TGFBR2 predispose patients to aggressive and widespread vascular disease.
Mutations in TGFBR1 and TGFBR2 or SMAD3 from DNA of remaining mummies can clarify one of the mysteries of Egyptian history.
The TGFBR1 (Transforming Growth Factor (Beta), Receptor 1) gene makes a receptor protein through which healthy cells receive messages from their neighbours, instructing them to carry out processes essential to normal growth and development.
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2.
The variation, on a gene known as TGFBR1, significantly increases a person's risk of developing the disease.
6] Nonstandard abbreviations: miRNA, microRNA; BMI, body mass index; LIFR, leukemia inhibitory factor receptor; VEGFA, vascular endothelial growth factor A; RT, reverse transcription; Ct, thermal cycle; TGFBR1, transforming growth factor-[beta] receptor; JAK-STAT, Janus kinase signal transducer and activator of transcription; MAPK, mitogen-activated protein kinase.
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- TGF-beta-related neurotrophic factor receptor 1
- TGF-beta-stimulated factor 1
- TGF-beta/activin signal transducer
- TGFB inducible early growth response
- TGFB-inducible early growth response 2
- TGFB-inducible early growth response protein 1
- TGFB-inducible early growth response protein 2
- TGFbeta Activated Kinase 1