TRICCTransfusion Requirements in Critical Care
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Looking at this question conversely, McIntyre et al (20) analyzed data from the TRICC trial, comparing outcomes in trauma patients who had been randomized to liberal and restrictive transfusion groups.
A recently published subset analysis of 357 patients with cardiovascular disease in the TRICC trial addressed the issue raised by Hebert et a1 (38) regarding whether transfusion does, in fact, decrease mortality in anemic critical care patients with cardiac disease.
Although the TRICC trial seems to have resolved the issue, the observations of Wu et al raise important questions.