| Acronym | Definition |
|---|
| TSL | Texas State Library |
| TSL | Teen Second Life (website) |
| TSL | Techsideline.com (website) |
| TSL | Transport Layer Security |
| TSL | Time Spent Listening |
| TSL | Troubles Spécifiques du Langage (French: Specific Language Disorders) |
| TSL | Tribunal Spécial pour Le Liban (French: Special Tribunal for Lebanon; UN Security Council) |
| TSL | The Svedberg Laboratory (Uppsala, Sweden) |
| TSL | Test Script Language (WinRunner) |
| TSL | Test and Set Lock |
| TSL | Thermally Stimulated Luminescence |
| TSL | Three Stage Lug (tires0 |
| TSL | Total Student Load (teacher-student ratio) |
| TSL | Transport Security Layer |
| TSL | Transmitter Studio Link |
| TSL | Type, Size and Location (preliminary design report for a bridge or highway structure) |
| TSL | Techno Superliner |
| TSL | Throat Seal Liquid (piston pump technology) |
| TSL | Tyovaen Sivistysliitto Tsl (Finnish; Workers' Educational Association) |
| TSL | Transfield Services Limited |
| TSL | Teinte, Saturation, Lumière (French: Hue, Saturation, Light) |
| TSL | Torque Sensing Link (Arctic Cat snowmobiles) |
| TSL | Tri-State Logic |
| TSL | Tri State Laboratories, Inc (Youngstown, OH) |
| TSL | Time and Space Ltd |
| TSL | Target Stock Level (economics) |
| TSL | Transfinite Systems, Ltd. |
| TSL | The Software Link, Incorporated |
| TSL | Time, Space, Logistics (military planning considerations) |
| TSL | Texas Shortline Railway |
| TSL | Theoretical Splice Line |
| TSL | Theme on Sustainable Livelihoods (International Union for Conservation of Nature) |
| TSL | Type Something Long |
| TSL | Temperature Switch, Low (piping and instrumentation) |
| TSL | Text Substitution Language (knowledge technology) |
| TSL | The Starting Line (band) |
| TSL | The Silver Lining (game) |
| TSL | Technical Services Limited (Hong Kong) |
| TSL | Turkish Super League (Turkish soccer club level) |
| TSL | Technical Services Librarian (various locations) |