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He notes there are several medications on the market to help control Type II diabetes, such as sulfonylureas, which help the pancreas produce more insulin; biguanides, which lessens the amount of glucose the liver produces; and thiazolidinediones, which helps make blood cells more receptive to insulin. Two classes of drugs can improve response to insulin and are used by prescription for type 2 diabetes--biguanides and thiazolidinediones. PPAR[gamma] regulates lipid and glucose homeostasis and is responsible for the antidiabetic actions of thiazolidinediones such as troglitazone. |
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