| Acronym | Definition |
|---|
| TSE | Tokyo Stock Exchange |
| TSE | Toronto Stock Exchange (TSX since April, 2002) |
| TSE | Tribunal Superior Eleitoral (Brazil) |
| TSE | Technical Support Engineer |
| TSE | Test of Spoken English (Educational Testing Service) |
| TSE | Tribunal Supremo Electoral (Supreme Electoral Tribunal, Guatemala) |
| TSE | Transactions on Software Engineering (IEEE publication) |
| TSE | Transmissible Spongiform Encephalopathy |
| TSE | Taiwan Stock Exchange |
| TSE | Terminal Server Edition (Microsoft NT Server) |
| TSE | Thomas Stearns Eliot (poet, critic, editor; 1888-1965) |
| TSE | Testicular Self-Examination (for cancer) |
| TSE | Turbo Spin Echo (MRI) |
| TSE | Toulouse School of Economics (France) |
| TSE | Total Solar Eclipse |
| TSE | Truck Stop Electrification |
| TSE | Twin-Screw Extruder (high-intensity mixer) |
| TSE | Traffic Safety Education |
| TSE | Treated Sewage Effluent |
| TSE | Total System Error |
| TSE | Travel Search Engine |
| TSE | Two Stroke Engine |
| TSE | Turk Standartlari Enstitusu (Turkish: Turkish Standards Institute; est. 1960) |
| TSE | Trans-Siberian Express |
| TSE | Taxe Spéciale d'Equipement (French: Special Equipment Tax) |
| TSE | Thayer School of Engineering (Dartmouth College) |
| TSE | The Sofia Echo (Bulgaria English Language Newspaper) |
| TSE | Terminal Server Emulation |
| TSE | Tissue-Specific Extinguisher |
| TSE | Technical Services for Electronics, Inc. (cable assembly manufacturer in Minnesota, USA) |
| TSE | Test Systems Engineering |
| TSE | Two-Step Estimator |
| TSE | Tension Stringing Equipment |
| TSE | Technical Surveillance Equipment |
| TSE | Topology State Element |
| TSE | Temperature Sensing Element (climate control) |
| TSE | Tritium Science and Engineering |
| TSE | Terminal Switching Exchange |
| TSE | Test Sequence Error |
| TSE | Threaded Small End |
| TSE | Transport Support Enabled |
| TSE | TAACOM Support Element |
| TSE | Tentative Symbol Estimation |
| TSE | Technical Support Enhanced |
| TSE | Tactical Support Element/Equipment |
| TSE | Texas Southeastern Railroad Company |
| TSE | TOC Support Element |
| TSE | Telephone Support Engineer |
| TSE | Thoughtstorm Entertainment |
| TSE | TRADOC Support Element |
| TSE | Tom Savage Explosion (band) |
| TSE | Typical Software Engineer |
| TSE | Traditional Search Engine (computing) |
| TSE | The Second Encounter (video game) |
| TSE | Technical Support Executive (various locations) |
| TSE | The Special Event (various locations) |