binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence.
ABBREVATIONS: ADAMTS = a disintegrin-like and metalloprotease domain with thrombospondin
type motifs; HUS = hemolytic-uremic syndrome; LD = lactate dehydrogenase; MAHA = microangiopathic hemolytic anemia; PT = prothrombin times; PTT = partial thromboplastin times; TMA = thrombotic microangiopathy; TT = thrombin times; TTP = thrombotic thrombocytopenic purpura; ULVWF = ultralarge VWF; VTEC = verotoxin-producing Ecoli; VWF = Von Willebrand factor; VWF-cp = VWF-cleaving protease.
03 in 17 chromosome 1 [Q09760] AA080628 phosphoribosylformylglycin amidine 7 synthase [P35421] AA080629 ORF 1130 [U20247] 6 AA080630 human thrombospondin
1 precursor 7 [P07996] AA080632 URP5 [1204259B] 16 AA080631 ERCC5 [D16305] 6 AA080635 murine erythroleukemia cardiac calcium 5 channel [U17869] AA080637 ORF gene product [X95373] 7 AA080638 latent transforming growth factor 8 beta-binding protein 3 precursor [A57293] AA080641 aminopeptidase [U35646] 28 AA080643 TO8A11.
Recently, an autoantibody against thrombospondin
type 1 domain containing 7A has been identified in PLA2R-Ab negative patients, though it only accounts for 8–14% of the PLA2R negative patients.
Especially, 581 genes that have Hanwoo-specific SNPs at least five are associated with immune activation by external stimuli, through epidermal growth factor-like domain (EGF-like domain), pleckstrin homology domain (PH domain), immunoglobulin subtype 2, and thrombospondin
(Figure 3) (Chen et al.
1 as a predictor of postoperative liver dysfunction.
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder that occurs due to deficiency of ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin
type 1 motif, member 13), which is a von Willebrand factor (VWF) cleaving protein.
76 Up TNXB Tenascin XB, tenascin-X 2 up THBS4 Thrombospondin
The thesis of the intensified enzymatic degradation of PGs/GAGs is confirmed by significantly higher concentrations of MMP-3 (metalloproteinase-3) or ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin
motifs 4), found in blood of JIA patients, which was reported in our earlier research [7, 9].
1] , GP1b[alpha] , vitronectin , and thrombospondin
254,261-265) Cancer-associated fibroblasts can also produce ECM molecules that enhance invasion, such as thrombospondin
1266 and fibronectin.
2,3) Matrix metalloproteinases and a disintegrin and metalloproteinase with thrombospondin
motifs (ADAMTS) play role in cartilage breakdown.