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TYMS
(redirected from Thymidylate Synthetase)

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AcronymDefinition
TYMSThymidylate Synthetase
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Decreased expression of six RNA species was seen at various time points in all cell strains analyzed: plasminogen activator (PLAT), centromere protein F (CPF), replication factor C (RFC3), thymidylate synthetase (TYMS), a putative mitotic checkpoint kinase (BUB1), and a gene of unknown function (GenBank accession no.
Differential gene expression in normal human mammary epithelial cells ... by Weston, Ainsley / Environmental Health Perspectives
Because the enzyme, thymidylate synthetase, plays a crucial role in the DNA synthesis of rapidly growing cells, many anticancer agents are designed to block its activity, thereby inhibiting tumor growth.
Enzyme structure to help drug design by Science News
 
 
 
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