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TPO |
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A number of thyroid genes, including NIS, thyroglobulin (Tg), and thyroid peroxidase (TPO), are stimulated by TSH and promote the synthesis of TH (Zoeller 2003). In the thyroid, minocycline accumulates in the follicular epithelium and colloid in benign, and even hyperplastic tissue as a result of the oxidative interaction between the drug and the enzyme thyroid peroxidase (figure 2). They act against the thyroid by inhibition of thyroid peroxidase. |
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