Resistance to cefotaxime, ceftazidime, ciprofloxacin, gentamicin, nalidixic acid, ticarcillin-clavulanic acid, and trimethoprim-sulfamethoxazole was above 85 Percent in both sets of isolates.
8 Isolates were tested against con ventional antimicrobials cefotaxime, ceftazidime (cephalosporins), nalidixic acid (quinolones), cip rofloxacin (flouroquinolones), gentamicin (amino glycosides), ticarcillin-clavulanic acid (augmented penicillins), and trimethoprim-sulfamethoxazole (sulphonamides); and antimicrobials used in treat ment of ESBL producing E.
ESBL was detected with a synergy test using disks containing CTX, ceftazidime, and ticarcillin-clavulanic acid
Antimicrobial drug susceptibility was performed with broth microdilution according to the Sensititre user manual and National Committee for Clinical Laboratory Standards (NCCLS) guidelines (7) for amikacin, amoxicillin-clavulanic acid, ampicillin, cefazolin, ceftiofur, ceftizoxime, chloramphenicol, enrofloxacin, gentamicin, tetracycline, ticarcillin-clavulanic acid, and trimethoprim-sulfamethoxazole.
Only 4 Salmonella Newport isolates from stranded seals were resistant to antimicrobial drugs; 3 isolates were resistant to ampicillin, with intermediate resistance to ticarcillin-clavulanic acid, and 1 isolate was resistant to amoxicillin-clavulanic acid and cefazolin.
and gentamicin were administered for 4 days until her neutrophil count increased to [is greater than] 1.
In this model, subcutaneous administration of piperacillin-tazobactam was found to protect against high-level VRE colonization, whereas ceftriaxone and ticarcillin-clavulanic acid (with antienterococcal activity equivalent to the cephalosporins) promoted high-level VRE colonization (Table 1).
In a citywide analysis of hospitals in the greater Cleveland area, the use of ticarcillin-clavulanic acid was associated with higher hospital rates of clinical VRE (26).