| Acronym | Definition |
|---|
| TSC | Thestreet.com (stock symbol) |
| TSC | Time Stamp Counter |
| TSC | Tuberous Sclerosis Complex |
| TSC | The Shopping Channel (Canada) |
| TSC | Technology Support Center |
| TSC | Terrorist Screening Center (Department of Homeland Security) |
| TSC | Tractor Supply Company |
| TSC | Technical Support Center |
| TSC | Texas Service Center |
| TSC | Theater Support Command |
| TSC | Technical Steering Committee |
| TSC | Time-Slot (Management) Channel |
| TSC | Theater Security Cooperation |
| TSC | Total Sanitation Campaign (India) |
| TSC | Teachers Service Commission (Kenya) |
| TSC | Telephone Service Center |
| TSC | The Second Coming |
| TSC | Theater Sustainment Command (replaces the Theater Support Command; US Army) |
| TSC | Technical Subcommittee |
| TSC | Technology Steering Committee |
| TSC | Teaching Support Centre |
| TSC | The Seniors Coalition |
| TSC | Thermally Stimulated Current |
| TSC | Training Support Center |
| TSC | Technology Service Corporation |
| TSC | Tactical Support Center |
| TSC | TRICARE Service Centers |
| TSC | Thyristor Switched Capacitor |
| TSC | Totally Self-Checking |
| TSC | Theater Signal Command |
| TSC | Technical Standards Committee (ACM) |
| TSC | Taiwan Semiconductor Co., Ltd. |
| TSC | The Sultan Center (Kuwait retailer) |
| TSC | Trenton State College (now College of New Jersey) |
| TSC | Tech Support Comedy |
| TSC | Transit Standards Consortium |
| TSC | Traffic Safety Committee |
| TSC | thiosemicarbazide |
| TSC | Trade Security Controls |
| TSC | Top Secret Clearance |
| TSC | Tamil Standard Code (font) |
| TSC | TKIP Sequence Counter |
| TSC | Tethered Spinal Cord |
| TSC | Teleservice Center (Social Security Administration) |
| TSC | Test System Controller |
| TSC | TSF Scope of Control |
| TSC | Training Systems Contract |
| TSC | thermally stimulated conductivity |
| TSC | Technical Service Coordinator |
| TSC | Total Safety Culture |
| TSC | Texas Senior Circuit (Swimming League) |
| TSC | Trunking System Controller (radiocomnunications) |
| TSC | Transportation System Center |
| TSC | Trade Show Center |
| TSC | Transit Switching Center |
| TSC | Two-Six Code |
| TSC | Telecommunications Support Contract |
| TSC | Training Steering Committee |
| TSC | The Speed Channel |
| TSC | Telecommunications Service Center |
| TSC | Total Ship Computing |
| TSC | Transformational Satellite Communications (System) |
| TSC | Time Slot Code (ITU-T) |
| TSC | Task Sequence Controller |
| TSC | TMDE Support Center |
| TSC | Time Sharing Control (task) |
| TSC | Total Square Correlation |
| TSC | Truck Safety Coalition |
| TSC | Training Status Code |
| TSC | Thompson Student Centre (Memorial University of Newfoundland) |
| TSC | Theater Surface Combatant |
| TSC | Targeted Service Coordinator |
| TSC | Technical Standardization Center |
| TSC | Tesomas Scout Camp (BSA) |
| TSC | Topology and Simulation Creator |
| TSC | Trojan Switching Center |
| TSC | Tanker Service Committee |
| TSC | The Solar Corporation |
| TSC | Tarokh, Seshadri, and Calderbank (4-state coding) |
| TSC | Tradeoff Study Control |
| TSC | Tag-Switched Controller (Cisco) |
| TSC | Technology Services Consultants |
| TSC | Tacit Storage Cache (Tacit Networks) |
| TSC | Time-Space Convergence |
| TSC | Transport Service Controller |
| TSC | Tanglin Sports Club (Singapore) |
| TSC | Test Suite Constraint |
| TSC | Transit Suez Canal |
| TSC | Time Slot Communication |
| TSC | Targeting Set Computer (LANTIRN) |
| TSC | Targeting Set Controller |
| TSC | Tactical/Technical Support Center |
| TSC | Tank Status Chart |
| TSC | Test Steering Committee |
| TSC | TEMO Simulations Conference |
| TSC | TBMCS Support Center |
| TSC | Transmission Systems Certification |
| TSC | Tool Safe Condition |
| TSC | Transportes San Cristobal SA (Guatemala cargo company) |
| TSC | Thread Scope PIurrent |
| TSC | Test Set Cards |
| TSC | Transmission Synchronizer Clutch |
| TSC | Triservice Support Center |
| TSC | Theoretical Sharp Corner (drafting) |
| TSC | Technology Support Crew |
| TSC | Transition Section Computer |