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TTR |
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Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo. Scientists who study PCBs have speculated that transthyretin has a special role in carrying PCBs to the fetus and especially its brain. Fx-1006A is a first-in-class, disease-modifying, small-molecule that is designed to inhibit the formation of amyloid deposits by binding and stabilizing the transthyretin protein (TTR), precluding misfolding and subsequent deposition of TTR. |
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