UTF1undifferentiated embryonic cell transcription factor 1
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Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors.
The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2.
We have not included other nuclear (AP-2[gamma], NANOG, UTF1, TLC1, etc) and cytoplasmic (Lin28 and IMP-3) pluripotency markers, since they broadly provide similar data and are not as widely used for diagnostic purposes.