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| Acronym | Definition |
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| USP | United States Pharmacopeia (United States Pharmacopeial Convention, Inc.) | | USP | Unit Sales Price | | USP | Universidade de Sao Paulo (University of Sao Paulo) | | USP | University of the South Pacific (Fiji, South Pacific) | | USP | Unique Selling Proposition | | USP | University of the Sciences in Philadelphia (Pennsylvania) | | USP | United States Penitentiary | | USP | United States Patent | | USP | Unique Selling Point | | USP | Universal Self-Loading Pistol (Heckler & Koch) | | USP | Union Suisse des Paysans (French: Swiss Farmers' Union) | | USP | Utah State Prison | | USP | Universal Storage Platform (Hitachi, Ltd.) | | USP | Universal Signaling Point (Nortel) | | USP | Ultraspiracle | | USP | Unique Sales Proposition | | USP | Ubiquitin-Specific Protease | | USP | Universal Service Provider | | USP | Ultrashort-Pulse (laser) | | USP | United Steel Products | | USP | University of Southern Philippines (Cebu City, Philippines) | | USP | Unsolicited Proposal | | USP | United States Postage | | USP | Universal Serial Port | | USP | User Stored Procedure | | USP | Universal Service Protocol | | USP | Usage Sensitive Pricing | | USP | Ultrasonic Spray Pyrolysis | | USP | Universal Service Plan | | USP | Universal Service Pistol | | USP | Universal Sampling Plan | | USP | Upsilon Sigma Phi | | USP | Usenet Service Provider | | USP | Universal Signaling Platform | | USP | User-to-User Signaling Process | | USP | Urban Services Plan | | USP | Usaha Simpan Pinjam (Indonesian: Business Savings and Loans) | | USP | Ubuntu System Panel (Linux) | | USP | United Surgical Partners International, Inc. (Addison, TX) |
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