| Acronym | Definition |
|---|
| UC | Upper Case |
| UC | University of Colorado |
| UC | University College (University of Toronto, Ontario, Canada) |
| UC | Up (Stage) Center |
| UC | Urbana-Champaign (Illinois, USA) |
| UC | University of Charleston (Charleston West Virginia) |
| UC | Universidad de Carabobo (Spanish: University of Carabobo; Venezuela) |
| UC | Undercover (TV show) |
| UC | Urgent Care |
| UC | Utica College (New York) |
| UC | Ulcerative Colitis |
| UC | United Center (Chicago arena) |
| UC | Union Council (Pakistan) |
| UC | Unified Command |
| UC | Université Catholique de Louvain |
| UC | Utility Computing |
| UC | Ursinus College (Collegeville, Pennsylvania) |
| uC | Micro-Controller |
| UC | Usual Care |
| UC | Unassisted Childbirth (birth without a medical professional in attendance) |
| UC | Unreal Championship (Xbox game) |
| UC | University Challenge (British television quiz show) |
| UC | Update Code |
| UC | User-Class |
| UC | Umbrella Corporation |
| UC | Urothelial Carcinoma |
| UC | Urban Cluster |
| UC | Urban Contemporary (music genre) |
| UC | Urban Council |
| UC | Uterine Contraction |
| UC | United Club |
| UC | Usability Center |
| UC | Upper Classman |
| UC | Utility Cargo (military aircraft designation) |
| UC | Utility Coordination |
| UC | Union Constitutionelle (French: Constitutional Union, Morocco) |
| UC | Universal Current |
| UC | Under-Crossing |
| UC | Uniform Calendar (Integrated Chronological Applications System) |
| UC | Ultra Cricket (game) |
| UC | User Correction |
| UC | Unity Check (stress analysis check) |
| UC | United Citizens Party (also seen as UCP) |
| UC | Upper Culmination |
| UC | Air Post Envelope or Letter Sheet (Scott Catalogue prefix; philately) |
| UC | University of Cantho (Vietnam) |
| UC | ULANA Certified |
| UC | Ultimate Climber (blog) |
| UC | Unprogressive Conservative |
| UC | Underfashion Club (Clinton Corners, NY) |
| UC | Union City (USA) |
| UC | Unconventional Computing (International Conference) |
| UC | Ultra Compact |
| UC | Universal Controller |
| UC | University of Coimbra |
| UC | Unity College (Maine) |
| UC | Undiscovered Country (Star Trek VI Movie) |
| UC | Under Construction |
| UC | Under Counter (blueprints) |
| UC | Unit Commitment |
| UC | Universal Century (Gundam animated series) |
| UC | Underpinning Contract |
| UC | Unconventional Couple (fanfiction) |
| UC | Universidade de Coimbra (Portugal) |
| UC | Universal Communicator (mobile phones which incorporate video and the internet) |
| UC | Universal Code |
| UC | University of Connecticut |
| UC | Undercharge |
| UC | Unarmed Combat (UK) |
| UC | Uncacheable (BIOS setting) |
| UC | Unique Calls (made) |
| UC | Universal Column |
| UC | Universidad Catolica |
| UC | Universidad de Concepcion (Chile) |
| UC | University Center |
| UC | University of California |
| UC | University of Chicago |
| UC | University of Cincinnati |
| UC | Unified Communications |
| UC | Unclassified |
| UC | University of Calgary (Alberta, Canada) |
| UC | University of Canberra (Australia) |
| UC | Unit Controller |
| UC | Universal Component |
| UC | University Christian (Jacksonville, Florida) |
| UC | Ultrasonic Consolidation |
| UC | Union College |
| UC | University of Cambridge (UK) |
| UC | Unemployment Compensation |
| UC | University of Canterbury |
| UC | Undercity (gaming, World of Warcraft) |
| UC | Unitary County (UK) |