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VKOR |
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Tecarfarin, like warfarin, is a selective inhibitor of VKOR, or vitamin K epoxide reductase enzyme, and has the same mechanism of anticoagulation action as warfarin. Tecarfarin, like warfarin, is a selective inhibitor of VKOR, or vitamin K epoxide reductase enzyme, and has the same mechanism of anticoagulation action as warfarin. An oral presentation entitled, "The CYP450 Inhibitor Fluconazole Increases Plasma Concentrations of both (R)-and (S)-Warfarin, but not ATI-5923, a Novel VKOR Inhibitor," described results of a clinical pharmacokinetic (PK) study conducted by ARYx. |
VKOR |
VKHD VKHS Vkhutein Vkhutemas VKI VKIFD VKISC VKK VKKL VKL VKLA VKLD VKLIT VKLJ VKM VKMC VKMCG VKMI VKMLA VKMO VKN VKNS VKO VKOD VKOR VKORCVKP VKPAI VKPB VKPD VKPM VKPR VKR VKRC VKRF VKRP VKRT VKS VKSA VKSC VKSJ VKSK VKSU VKT VKTI VKtRS VKU VKUMC VKUT | |||||
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