| Acronym | Definition |
|---|
| VCS | Veritas Cluster Server |
| VCS | Version Control System |
| VCS | Vice City Stories (Grand Theft Auto game) |
| VCS | Video Computer System |
| VCS | Veterans for Common Sense |
| VCS | Vatican City State |
| VCS | Veterinary Cancer Society |
| VCS | Video Communication Systems (Nuremberg, Germany) |
| VCS | Video Communication Systems AG |
| VCS | Victory Christian School |
| VCS | Verilog Compiled Simulator (logic simulator, compiles Verilog source code) |
| VCS | Virginia Class Submarine |
| VCS | Video Conferencing Service |
| VCS | Vehicle Control System |
| VCS | Vienna Christian School (Austria) |
| VCS | Video Compression System |
| VCS | Virtual Carrier Sensing |
| VCS | Voluntary Correction of Operational Failures Standardized (IRS) |
| VCS | Virtual Channel Switch |
| VCS | Vapor Cooled Shield |
| VCS | Visually Coupled Systems |
| VCS | Varee Chiangmai School (Thailand) |
| VCS | Vertical-Coupler Switch |
| VCS | Voice-Coil Stage |
| VCS | Velocità di Conduzione Sensitiva (Italy) |
| VCS | Navy Cruiser Scouting Squadron (US Navy aviation unit designation used from 1920s to 1950s) |
| VCS | Visual Computing Services, Ltd |
| VCS | Vehicle Computer Simulation |
| VCS | Video Clutter Suppression |
| VCS | Vendor Communications System |
| VCS | Visual Classroom Scheduling (educational software) |
| VCS | Videochat Studios |
| VCS | Vicks Cough Suppressant |
| VCS | Virtual-slot Control Strategy |
| VCS | View Control System |
| VCS | Visual Client Side |
| VCS | VOTRICS Communication System (Alcatel) |
| VCS | Virginia and Carolina Southern Railroad |
| VCS | Vieux Cochons Seillonnais (French: Old Pigs Seillons; cycling club; Seillons-Source-d'Argens, France) |
| VCS | Valuation Control Section |
| VCS | Vestibular Caloric Stimulation |
| VCS | Visualization and Computation System |
| VCS | Voice Call Sign |
| VCS | Voice Communications Subsystem |
| VCS | Voice Control System |
| VCS | Virtual Circuit Switch(es) |
| VCS | Virtual Communications Service (AT&T) |
| VCS | Virus Control System (Trend) |
| VCS | Virtual Controller Software |
| VCS | Vitalize Consulting Solutions (various locations) |
| VCS | Video Customer Service |
| VCS | Voice Controlled Services |
| VCS | Voluntary Carbon Standard (air pollution) |
| VCS | Video Conference System |
| VCS | Voice Communications System |
| VCS | Village Charter School (various locations) |
| VCS | Visual Comparison Standards (NMWR) |
| VCS | Voluntary and Community Sector |