2010) have studied gelatinases MMP-2 and MMP9 in both normal tissues and the ones with benign and malignant lesions in different species, including dogs, since MMPs are proteolytic enzymes capable of degrading components of connective tissue, such as the ECM, during tissue remodeling, which occurs in physiologic and pathologic conditions (EGEBLAD & WERB
, 2002; MOOK et al.
Considerando que a glandula mamaria e o unico orgao em que o desenvolvimento de ductos ocorre apos a fase embrionaria (WISEMAN & WERB
, 2002), e possivel a participacao da Cyr61 na promocao da proliferacao e adesao das celulas epiteliais dos ductos mamarios, ja que essa proteina esta envolvida nos processos de mediacao da migracao e adesao celular, operando como fator de crescimento em diversas situacoes (XIE et al.
Animators from around the globe are also providing content of all styles and lengths - from quirky, stop-motion shorts like Poor Daisy by Werbs to 3D epics like Raven by Daredevil Films.