| Acronym | Definition |
|---|
| WEC | Web-Empowered Church (open source web-ministry system; Ohio) |
| WEC | World Extreme Cagefighting (mixed martial arts sport) |
| WEC | World Energy Council |
| WEC | World Enduro Championship (FIM Motorcycle Event) |
| WEC | Wisconsin Energy Corporation (Milwaukee, WI) |
| WEC | World Environment Center |
| WEC | Wildlife Ecology and Conservation (University of Florida) |
| WEC | Westinghouse Electric Company |
| WEC | World Endurance Championship |
| WEC | Wave Energy Converter |
| WEC | Web Extender Client (Microsoft) |
| WEC | Washington Environmental Council |
| WEC | Whole Earth Catalog |
| WEC | Women Entrepreneurs of Canada (Toronto, Ontario, Canada; est. 1992) |
| WEC | World Energy Conference |
| WEC | Wind Energy Conversion |
| WEC | Western Engineering Competition (annual; Canada) |
| WEC | Water and Energy Commission (Nepal) |
| WEC | World Enduro Canada (motorcycle racing) |
| WEC | Worldwide Evangelisation for Christ |
| WEC | Waterborne Education Center (Texas) |
| WEC | World Education Council (various locations) |
| WEC | Wong Engineering Corporation (Malaysia; est. 1982) |
| WEC | Wall, Einhorn, & Chernitzer, PC |
| WEC | Window Edge Coordinate |
| WEC | Wartime Engagement Criterion |
| WEC | Work of Engineering Construction (UK) |
| WEC | Watermelon Eating Contest |
| WEC | War Ensemble Clan (gaming) |
| WEC | West Executive Controller |
| WEC | Western Economic Council (Cincinnati, OH) |
| WEC | Wider Economic Cost |
| WEC | Wonnarua Elders Corporation (Australia) |
| WEC | Western Electric Corporation |