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However, most malignant brain tumors recur within a short period of time and a second course of whole brain radiation therapy is rarely an option due to the high risk of damage to healthy brain tissue. Surgery and whole brain radiation are proven therapies for brain metastasis, but whole brain radiation therapy has potential to result in delayed neurotoxicities, such as memory loss. The statements were materially false and misleading when made because they failed to disclose or indicate the following: (i) that the Company's study failed to demonstrate benefits of its lead clinical candidate, RSR13, plus whole brain radiation therapy (" |
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