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The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene. Chapter 6 addresses diseases with several types of movement disorders, including Wilson disease, Hallervorden-Spatz disease, multiple system atrophies, and progressive calcification of the basal ganglia. Aberrations in molecular trafficking are implicated in many diseases, including Alzheimers, von Willebrands, cystic fibrosis, Huntington, ALS, Fabry, Batten, and Wilson diseases. |
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