The patients were assessed on the HDRS, YMRS
, and GAF.
The main outcomes of interest were changes in YMRS
and PANSS scores.
7) Thymectomy, n (%) 18 (60) 10 (48) Antidepressant therapy, n (%) 6 (20) 4 (19) Fluoxetine 20 mg daily, n (%) 3 (10) 3 (10) Amitriptyline 25 mg daily, n (%) 3 (10) 1 (3) Neuropsychiatric assessments BDI-II score, mean (SD) 16 (9) 18 (10) HAM-A score, mean (SD) 14 (9) 14 (9) BPRS score, mean (SD) 12 (7) 13 (7) YMRS
score, mean (SD) 4 (4) 4 (4) Suicidal ideation, n (%) 9 (30) 7 (33) Psychiatric referral, n (%) 14 (46) 11 (52) Thymoma MG p-value (n = 9) Male/female 3/6 0.
3 hours after recovery from general anaesthesia after each ECT simultaneously with YMRS
Other variables which differed significantly across groups, namely, the duration of illness, age at onset, and YMRS
and BPRS scores, were also included as covariates.
Se utilizo la escala de depresion de Hamilton (HDRS) de 17 items (22) y la escala de mania de Young (YMRS
) (23), ambas validadas al espanol, con el objetivo de comprobar los criterios de eutimia segun HDRS < 7 y YMRS
The primary efficacy measure in the 3 trials was a change from baseline in the total YMRS
score at the end of Week 3, compared with placebo.
His manic symptoms showed significant improvement following the removal of the tumor but he had residual mild impairment in his concentration, memory and abstract thinking: three months after the surgery his YMRS
score was 4 (out of 60) and his MMSE was 24 (out of 30).
28), whereas the mean YMRS
total score was lower than those without OCD (p = 0.
Changes in the YMRS
or BPRS Positive Symptom score at 40 minutes did not significantly correlate with HDRS improvement at any time point with ketamine.
(Young Mania Rating Scale) score was 17 on presentation to us.
He scored 8 on the YMRS
upon discharge, and had no depressive features at the time.