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ZNF |
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Characterization and mapping of human genes encoding zinc finger proteins. Dow AgroSciences LLC has licensed zinc finger DNA-binding protein (ZFP) technology from Sangamo BioSciences Inc. Some of the targets that might be important include structural elements (such as the highly conserved zinc finger motif of the HIV nucleocapsid or the viral enzymes integrase and RNase H), regulatory and accessory proteins, processes (such as transcription, nuclear import and export of viral nucleic acid, and macromolecular interactions), and host targets (adhesion molecules, transcription factors, apoptosis, and signaling pathways). |
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