Du, Total alkaloids of Corydalis saxicola bunting inhibits migration of A549 cells by suppressing
Cdc42 or Vav1, Oncol.
The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of
Cdc42. Proc Natl Acad Sci USA.
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes.
The drug mimics the action of an important gene called
CDC42 that helps regulate blood stem cells.
Based on figure 2, PAX5 transcription factor and genes including ARID1A,
CDC42 and LPPR4 were highlighted as the most important units within the genes network with more interconnected links (Figure 2).
Dicha regulacion se realiza mediante la expresion de algunas proteinas como la Rac1 y
Cdc42, las cuales interactuan directamente con los mecanismos de la translocacion nuclear, generando cambios dinamicos en la disposicion de los microtubulos y actina citoplasmaticos.
The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein
Cdc42. Proc.
Moreover, the implantation of blastocysts into the endometrial stroma cells is regulated by the Rho GTPases RhoA, Rac 1 and
Cdc42 (Grewal et al., 2010).
Indeed, while cholesterol efflux in cholesterol-depleted RAW 264.7 cells is as small as less than 1% of total cholesterol, the knockdown of dynamin-2, or ADP-ribosylation factor 6 (Arf6), or
Cdc42 reduces it even further [15].
In mesenchymal stem cells (MSCs), FAK signaling is interconnected with various pathways including mitogen-activated kinases (MAPKs) and Rho-family GTPases RhoA, Rac, and
Cdc42 [12].
The Rho family of GTPases, including Rho1, Rac1, and
Cdc42, regulates actin dynamics.