'TRPC6 binds to and activates
calpain, independent of its channel activity, and regulates podocyte cytoskeleton, cell adhesion and motility' by L Farmer et al in Journal of the American Society of Nephrology (JASN).
For the determination of the general structure and 3 kinds of antibodies (
calpain 1, caspase-3 and GABA-A receptor alpha 1), 16 serial preparations (960 sections in total) were prepared from each tissue.
The autolysis of meat occurs with the active participation of lysosome enzymes-cathepsins and
calpains (Hope-Jones, 2010).
BLD-2660 is a best-in-class
calpain inhibitor with robust anti-fibrotic activity in vivo.
Phelix Therapeutics continues to advance and commercialize the
Calpain Inhibitor research and development work of Dr.
Association between yearling weight and calpastatin and
calpain loci polymorphism in Iranian Zel sheep.
Spencer, "
Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance," Neuromuscular Disorders, vol.
Calpain, also known as calcium-dependent protease system, is an effective molecule reacting to an intracellular calcium signal, calpain-1, which has been shown to selectively cleave some apoptotic proteins (e.g.
Using human RPE-derived ARPE-19 cell line, we analyzed thrombin-induced [[Ca.sup.+2]]i increase and demonstrated that the calcium-dependent activation of [micro]-calpain and the subsequent degradation of [alpha]-spectrin by
calpain significantly decrease PAR1 expression at the cell membrane.