| Acronym | Definition |
|---|
| FOC | Full Operational Capability (US DoD acquisition term to depict when a specific activity reaches maturity) |
| FOC | Friends of the Constitution |
| FOC | Faculty of Commerce (various locations) |
| FOC | Focus |
| FOC | Fall of Cybertron (gaming) |
| FOC | Federation of Churches |
| FOC | Fiber Optic Center |
| FOC | Fellowship of Christians (various organizations) |
| FOC | Free Of Charge |
| FOC | Foreign Oil Company |
| FOC | Friend of the Court |
| FOC | Facilitating Organizational Change |
| FOC | Fort Omaha Campus (Metropolitan Community College; Omaha, NE) |
| FOC | Freedom of Creation (3D printing; Amsterdam) |
| FOC | Federal Office of Culture (Switzerland) |
| FOC | Flux Oriented Control |
| FOC | Forum of Conscience (human right group) |
| FOC | Freedom Online Coalition (intergovernmental coalition) |
| FOC | Franchise Offering Circular |
| FOC | Florentine Opera Company (Milwaukee, WI) |
| FOC | Field Oriented Control |
| FOC | Fail over Cluster |
| FOC | Force Output Compare |
| FOC | First Options of Chicago (Chicago, IL) |
| FOC | Flag of Convenience |
| FOC | Family Outreach Center |
| FOC | Foyer Occupationnel (French: Occupational Center) |
| FOC | Full and Open Competition |
| FOC | Fiber Optic Cable |
| FOC | Flight of the Conchords (TV series) |
| FOC | Factory Outlet Center |
| FOC | Free of Cost |
| FOC | Faint Object Camera (Hubble Telescope) |
| FOC | Finance and Operations Committee (various organizations) |
| FOC | Freedom of Choice |
| FOC | Firm Order Confirmation |
| FOC | Fisheries and Oceans Canada |
| FOC | Fruit of the Crime |
| FOC | Front of Center (archery) |
| FOC | First Order Condition (mathematics) |
| FOC | Ferrari Owners Club |
| FOC | Final Operational Capability |
| FOC | Fujitsu Optical Components (Japan) |
| FOC | Fuji Oil Company, Ltd. (Japan) |
| FOC | Fiber Optic Communications |
| FOC | Firm Order Commitment |
| FOC | Fiscal Oversight Committee (various organizations) |
| FOC | Family of Companies |
| FOC | Flight Operation Center |
| FOC | Fiber Optic Connector |
| FOC | Fixed Order Cycle (finance) |
| FOC | Flight Operations Center |
| FOC | Fold Out Cover (vinyl record feature) |
| FOC | First Of Class |
| FOC | Forward of Center (archery) |
| FOC | Fight of Characters (Warcraft III; computer game) |
| FOC | Foreign Operating Corporation |
| FOC | Fresh Out Crew |
| FOC | Follow-On Contract |
| FOC | Field Operations Center |
| FOC | Friends of Carlotta (from movie 'Dead Men Don't Wear Plaid') |
| FOC | FEMA Operations Center |
| FOC | Fiber Optic Component |
| FOC | Festival of Cricket |
| FOC | Fear Of Commitment |
| FOC | Fabrication d'Objets en Caoutchouc et Plastique (French: Manufacture of Rubber and Plastic Objects) |
| FOC | Father of Child |
| FOC | Forward Only Conversion (radio control cars) |
| FOC | Future Operational Capability |
| FOC | Father of Chapel (senior trades union official SOGAT & NGA) |
| FOC | Federation Orientation Committee (University of Waterloo, California) |
| FOC | Force of Contraction |
| FOC | Fuzhou City (China) |
| FOC | Friends of Christ |
| FOC | Flex-on-Cap |
| FOC | Follower of Christ |
| FOC | Face of Curb |
| FOC | Frontal-Occipital Circumference |
| FOC | Force Organization Chart (gaming) |
| FOC | Fell Off Chair |
| FOC | First Class CW Operator's Club (UK) |
| FOC | Flux Cutting (welding) |
| FOC | Full Operational Clearance |
| FOC | Fact or Crap |
| FOC | Front-Of-Counter |
| FOC | Friends of Colombia (Peace Corps alumni) |
| FOC | Flat Over Crest (Rally Car Racing) |
| FOC | First Office Call (medical appointment) |
| FOC | FORSCOM Operations Center |
| FOC | Financial Operations Center |
| FOC | Fall Off Chair |
| FOC | Future Operating Capability |
| FOC | Facility Operations Center |
| FOC | Farthest-On Circle |
| FOC | Factor of Cooperation |
| FOC | Fall Out of Chair |
| FOC | Flight Operations Committee (IATA) |
| FOC | Festival of Celebration |
| FOC | Fleet Operations Center |
| FOC | Factory of Champions (San Antonio, TX) |
| FOC | Foreign Object Check |
| FOC | Fear Of Controlling (air traffic control) |
| FOC | Friends of Cry |
| FOC | Furthest-On Circle |
| FOC | Facilities Operations Committee |
| FOC | Firing Officer Console |
| FOC | Full Of Choice (Malacca, Malaysia shop) |
| FOC | Foreign Operating Companies |
| FOC | Fiber Optical Characterization |
| FOC | Fin Opener Crank (missile assembly tool) |
| FOC | Fundamental Orders of Connecticut |
| FOC | Friends of the Committee (various organizations) |
| FOC | Flash-on-Camera (photography) |
| FOC | Future Operations Cell |
| FOC | Friends of the Carpenters (non-profit ministry) |
| FOC | Foundation for Orphaned Children (Kenya) |
| FOC | Fill or Cancel |
| FOC | Free Organic Carbon |