| Acronym | Definition |
|---|
| HPA | Health Protection Agency (UK) |
| HPA | Human Protein Atlas |
| HPA | Horizontal Pod Autoscaler (computing) |
| HPA | Hectopascal |
| HPA | Hawaii Preparatory Academy |
| HPA | High Power Amplifier |
| HPA | Host Protected Area (hard disks) |
| HPA | Harry Potter Alliance (fiction) |
| HPA | Hybridization Protection Assay (biology) |
| HPA | Host Protected Area |
| HPA | High Performance Architecture |
| HPA | Hamburg Port Authority (Germany; est. 2005) |
| HPA | High Pressure Air |
| HPA | High Physical Activity (exercise) |
| HPA | High Point Academy (middle school; Pasadena, CA) |
| HPA | High Performance Applications |
| HPA | High Performance Analog |
| HPA | Health Policy and Administration (education program) |
| HPA | High Performance Automotive |
| HPA | Hydraulic Project Approval |
| HPA | Hazardous Products Act |
| HPA | Hydrocarbures Polycycliques Aromatiques (French: Polycyclic Aromatic Hydrocarbons) |
| HPA | Human Platelet Antigen |
| HPA | Historic Preservation Agency |
| HPA | Illinois Historic Preservation Agency |
| HPA | High Performance Application |
| HPA | High Performance Addressing |
| HPA | Human-Powered Aircraft |
| HPA | High Performance Aircraft (aviation) |
| HPA | Home Price Appreciation |
| HPA | Hawaii Paroling Authority |
| HPA | HomePlug Powerline Alliance |
| HPA | Haunted Pennsylvania (website) |
| HPA | Hanoi Plan of Action |
| HPA | Hamilton Port Authority (Canada) |
| HPA | Health Plan Administrator |
| HPA | High-Profile Attack (war) |
| HPA | Health Planning Agency (various locations) |
| HPA | Hawaii Psychological Association |
| HPA | Hospital Partners of America (Charlotte, NC) |
| HPA | Health Policy Authority |
| HPA | Humberside Police Authority (UK) |
| HPA | Hermes Precisa Australia |
| HPA | Hard Physical Address |
| HPA | High Payoff Activity |
| HPA | Higher-order Path Adaptation |
| HPA | Hyperphenylalaninemia, Mild |
| HPA | Horse Protection Act of 1970 |
| HPA | Hydraulic Power Assist (Ford) |
| HPA | High Pressure Alarm |
| HPA | Hawaii Publishers Association (Kaneohe, HI) |
| HPA | Hydroxy-Propyl Acrylate |
| HPA | Homeowner's Protection Act of 1998 |
| HPA | Hypophyseal-Pituitary Axis |
| HPA | Histoplasma Capsulatum Polysaccharide Antigen |
| HPA | Horizontal Planar Array |
| HPA | Home Page Award |
| HPA | Higher Polyamine (chemical) |
| HPA | Head of Procuring Activity |
| HPA | Half-Power Angle |
| HPA | Hereditary Papulotranslucent Acrokeratoderma |
| HPA | Head of Processing Activity |
| HPA | Hydraulic Power Assembly |
| HPA | Hypothalamic-Pituitary-Adrenal/Adrenocortical |