| Acronym | Definition |
|---|
| IRI | Information Reuse and Integration |
| IRI | Islamic Republic of Iran |
| IRI | International Republican Institute (formerly National Republican Institute for International Affairs, NRIAA, Washington DC) |
| IRI | Integrated Resources, Inc. (various locations) |
| IRI | International Roughness Index (describes road roughness) |
| IRI | International Research Institute for Climate and Society (Columbia University, New York) |
| IRI | Interpersonal Reactivity Index (psychology) |
| IRI | Immunoreactive Insulin |
| IRI | Interactive Radio Instruction |
| IRI | Industrial Research Institute |
| IRI | Istituto per la Ricostruzione Industriale (Italy) |
| IRI | International Research Institute for Climate Prediction |
| IRI | Industrial Risk Insurers (Employers Reinsurance Corporation group of companies, a part of the General Electric Company) |
| IRI | Ionospheric Research Instrument |
| IRI | Instituto Republicano Internacional (Spanish: International Republican Institute; various locations) |
| IRI | Industrial Research and Innovation (various organizations) |
| IRI | Internationalized Resource Identifier |
| IRI | Initial Requester Id |
| IRI | Ischemic Renal Injury |
| IRI | Indiana Robotics Invitational (Indianapolis, IN) |
| IRI | International Reference Ionosphere |
| IRI | Initiative and Referendum Institute (various locations) |
| IRI | Informal Reading Inventory |
| IRI | Internet Research Institute, Inc (Japan) |
| IRI | Information Resources, Incorporated |
| IRI | Intensive Reading Instruction (various locations) |
| IRI | Information Research, Inc. (various companies) |
| IRI | Interfaculty Reactor Institute (Delft, NL) |
| IRI | Intercept Related Information |
| IRI | Industrial Reporting, Inc. (Ashland, VA) |
| IRI | Insulin Resistance Index |
| IRI | Interfacultair Reactor Instituut |
| IRI | Industrial Risk Insurance |
| IRI | Infinity Resources, Inc. (marketing) |
| IRI | Institut des Relations Internationales |
| IRI | Interception Related Information (telecommunications) |
| IRI | In Ranks Inspection |
| IRI | Insurance Recovery International |
| IRI | Inertial Reference Interface |