| Acronym | Definition |
|---|
| MLC | Multi-Level Cell |
| MLC | Maritime Labour Convention (International Labour Organization) |
| MLC | Machine Learning Classifier (algorithm) |
| MLC | Myosin Light Chain |
| MLC | Midlife Crisis (slang; also an Ohio band) |
| MLC | Metropolitan Learning Center (various locations) |
| MLC | Martin Luther College (New Ulm, MN) |
| MLC | Medico-Legal Case |
| MLC | Mainland China |
| MLC | Mid-Life Crisis |
| MLC | Multileaf Collimator |
| MLC | Mini Line Card |
| MLC | Multi Level Coding |
| MLC | Multi Layer Coating |
| MLC | Multi Link Control Field |
| MLC | Multi Layer Cell |
| MLC | Multi Level per Cell |
| MLC | Medium Level Controller |
| MLC | Multi Layer Chip |
| MLC | Marketing Leadership Council |
| MLC | Movement for the Liberation of Congo (Congolese rebel group) |
| MLC | Methodist Ladies' College (Australia) |
| MLC | Math Learning Center |
| MLC | Meat and Livestock Commission (United Kingdom) |
| MLC | Montessori Learning Center (various locations) |
| MLC | Minimal Link Condition (linguistics) |
| MLC | Mississippi Library Commission |
| MLC | Medical Licensing Council (Biafra) |
| MLC | Multilayer Ceramic |
| MLC | Michigan Library Consortium |
| MLC | Macrophage-Like Cell |
| MLC | Multilayer Coating (chemical materials) |
| MLC | Mixed Lymphocyte Culture |
| MLC | Manitoba Lotteries Corporation |
| MLC | Midland Lutheran College (now Midland University; Fremont, NE) |
| MLC | Multi-Loop Controller |
| MLC | Member of Legislative Council |
| MLC | Models of Life Contingencies (mathematics) |
| MLC | Maximum Likelihood Classification |
| MLC | Maximum Load Current (electricity) |
| MLC | Metal-Ligand Complex |
| MLC | Medical Licentiates Consortium |
| MLC | Military Load Classification |
| MLC | Most Likely Case (risk assessment) |
| MLC | Merrill Lynch Canada |
| MLC | Missouri Loves Company (tournament) |
| MLC | Maintenance and Logistics Command |
| MLC | Master Labor Contract |
| MLC | Moray Leisure Centre (UK) |
| MLC | Mobile Location Centre (GSM, CDMA, mobile communications) |
| MLC | Monthly License Charge |
| MLC | Major Landing Craft (US Navy) |
| MLC | Meters/Liquid Column |
| MLC | Mobile Launcher Computer |
| MLC | Mid-Grade Learning Continuum (US Army) |
| MLC | Margate Language Centre (UK) |
| MLC | Management Leadership Conference |
| MLC | Monarchist League of Canada |
| MLC | Mailing List Committee (various organizations) |
| MLC | Mortgage Loan Company (real estate finance) |
| MLC | Mixed Low Copper |
| MLC | Megalencephalic Leukoencephalopathy with Subcortical Cysts |
| MLC | Multi-Level Coding |
| MLC | Masonic Leadership Center |
| MLC | Midwife Led Care (healthcare) |
| MLC | Military Liaison Committee |
| MLC | Medical Licensing Commission (UK) |
| MLC | Marianist Lay Communities |
| MLC | Multiple Logical Channel |
| MLC | Multimedia Language Center (various universities) |
| MLC | Main Lobe Clutter (radar) |
| MLC | Memory Load Command |
| MLC | Morgan Library Collection |
| MLC | Ministry of Lectors and Commentators (Catholicism) |
| MLC | Multicultural Leadership Council |
| MLC | Missouri Lottery Commission |
| MLC | Medical Law Consultant |
| MLC | Milirat Landing Craft (US Navy) |
| MLC | Mailing List Code |
| MLC | Myanma Language Commission (Myanmar) |
| MLC | Multi-Link Control |
| MLC | Modular Loop Carrier |
| MLC | Magnetic Leader Card (NASA) |
| MLC | Main Lobe Cancellation |
| MLC | Men's Last Choice |
| MLC | Missile Launch Console |
| MLC | Mobile Liaison Cell |
| MLC | Missile to Launcher Contactor |
| MLC | Management Level Chart/Code |
| MLC | Mad Life Crisis (band) |
| MLC | Chief Molder (Naval Rating) |