Neuropeptide Y- - A novel brain peptide with structural similarities to
peptide YY and pancreatic polypeptide.
Glucagon-like peptide 1, oxyntomodulin,
peptide YY, and pancreatic polypeptide.
Batterham, "The role of
peptide YY in appetite regulation and obesity," The Journal of Physiology, vol.
Sainsbury, "Neuropeptide Y and
peptide YY: important regulators of energy metabolism," Current Opinion in Endocrinology, Diabetes, and Obesity, vol.
Cirilo et al., "Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin,
peptide YY, and insulin," The Journal of Clinical Endocrinology & Metabolism, vol.
Wolever, "Acute effects of intravenous and rectal acetate on glucagon-like peptide-1,
peptide YY, ghrelin, adiponectin and tumour necrosis factor-[alpha]," British Journal of Nutrition, vol.
Both the conventional and delayed-release formulations of metformin increased GLP-1 and
peptide YY levels to a similar extent.
Gomis, "Circulating
peptide YY, weight loss, and glucose homeostasis after gastric bypass surgery in morbidly obese subjects," Annals of Surgery, vol.
Glucose-dependent insulinotropic peptide (GIP),
peptide YY (PYY), and glucagon-like peptide-1 (GLP-1) are all gut-derived signaling molecules that control appetite.
It is a polypeptide hormone consisting of 36 amino acids and is called
peptide YY (PYY) because it is a polypeptide having an N-terminal tyrosine (Y) and a C-terminal tyrosine (Y) (7).
In particular, the gut peptides ghrelin and
peptide YY (PYY) are of interest because they appear to regulate hunger and food intake for up to 24-hours (Wren et al., 2001) and are not specifically controlled by body fat stores, as are the adipokines leptin and adoponectin (Cummings and Overduin, 2007).