| Acronym | Definition |
|---|
| SEM | Search Engine Marketing |
| SEM | SEO (Search Engine Optimization) E-Marketing |
| SEM | Search-Engine Marketing |
| SEM | Scanning Electron Microscope |
| SEM | Scanning Electron Microscopy |
| SEM | Structural Equation Modeling |
| SEM | Strategic Enterprise Management |
| SEM | Safety and Environmental Management (various organizations) |
| SEM | Seminary |
| SEM | Slovenski Etnografski Muzej (Slovenian: Slovenian Ethnographic Museum) |
| SEM | Standard Error of Mean |
| SEM | Search Engine Management |
| SEM | Space Environment Monitor |
| SEM | Semitic |
| SEM | Structural Engineering and Mechanics (journal; Techno Press) |
| SEM | Samuel Eliot Morison (historian) |
| SEM | Strategic Enrollment Management |
| SEM | Specific Equipment Model |
| SEM | Submissions on Enforcement Matters (Commission for Environmental Cooperation) |
| SEM | Scuola Estetica Moderna (Italian: Modern Beauty School) |
| SEM | Société d'Économie Mixte (French: Mixed Enterprise Company) |
| SEM | Simultaneous Equation Model |
| SEM | Software Engineering and Middleware |
| SEM | Security Event Management |
| SEM | Silver Elite Master (gaming) |
| SEM | Service Ecoles-Médias (French: Schools Media Service; Switzerland) |
| SEM | Slovene Ethnographic Museum (Slovenia) |
| SEM | Sequential Excavation Method (tunnel engineering) |
| SEM | Society for Ethnomusicology |
| SEM | Social Enterprise Management |
| SEM | System Error Message |
| SEM | Symantec Event Manager |
| SEM | Scalar Equation Method |
| SEM | Scripture Encoding Model |
| SEM | Server Enterprise Manager |
| SEM | SQL Enterprise Manager (Microsoft client for SQL Server) |
| SEM | Schoolwide Enrichment Model |
| SEM | Superior Energy Management |
| SEM | Single Electricity Market (Ireland and UK) |
| SEM | Society for Experimental Mechanics, Inc. |
| SEM | School of Economics and Management |
| SEM | Security Engineered Machinery |
| SEM | Semicarbazide |
| SEM | Spectral Element Method |
| SEM | Single Economic Market (various locations) |
| SEM | Spolocenstvo Evanjelickej Mladeze (Slovak religious organization) |
| SEM | Security Event Manager |
| SEM | Standard Error of the Means |
| SEM | Selma-Smithfield (Amtrak station code; Selma-Smithfield, NC) |
| SEM | Systems Engineering Management |
| SEM | Science and Engineering of Materials |
| SEM | systolic ejection murmur (cardiology) |
| SEM | Sports Entertainment Media |
| SEM | Space Experiment Module |
| SEM | Sponsored Educational Materials (public relations) |
| SEM | Schlegel Electronic Materials (various locations) |
| SEM | Saint Etienne Métropole (French: Saint Etienne Metropolis; Loire, France) |
| SEM | Senior Engineering Manager |
| SEM | Saccadic Eye Movement |
| SEM | Sports & Entertainment Marketing |
| SEM | Strategic Environmental Management |
| SEM | Sumika Electronic Materials (Sumitomo Chemical Co. Ltd.) |
| SEM | Slow Eye Movements |
| SEM | Systems Engineering Manager |
| SEM | Singularity Expansion Method |
| SEM | Sample Exchange Mechanism (US NASA) |
| SEM | Sound and Efficient Management (EU) |
| SEM | Stock Exchange of Mauritius Ltd |
| SEM | Services Execution Management |
| SEM | Subsea Electronics Module |
| SEM | Spacecraft Equipment Module (US NASA) |
| SEM | Structural, Electrical and Mechanical (architectural engineering) |
| SEM | Seattle Emergency Management (Seattle, WA) |
| SEM | Secondary Emission Monitor |
| SEM | System Engineering Methodology |
| SEM | System Engineering Manual |
| SEM | Sensitivity Equation Method |
| SEM | Spherical Earth Model |
| SEM | Standard Extrapolation Method |
| SEM | Single-Ended Mode |
| SEM | Search Engine Master |
| SEM | Skin, Eyes or Mouth (herpes infection) |
| SEM | Solution Engagement Manager (Salesforce.com, Inc.) |
| SEM | Sudan Evangelical Mission |
| SEM | Socially and Emotionally Maladjusted |
| SEM | Site Engineering and Maintenance (Department) |
| SEM | Simulation, Engineering, and Modeling |
| SEM | Storm Electrification Model |
| SEM | Standard Equipment Modules |
| SEM | Evangelical Seminary of Madrid |
| SEM | System Engineering and Modeling |
| SEM | Solar Environmental Monitor |
| SEM | Softcopy Exploitation Management |
| SEM | Station Emulation Mode |
| SEM | Scheduled Event Management (Sprint) |
| SEM | Secteur Extra-Métropolitain (French: Extra-Metropolitan Area; French Social Security) |
| SEM | Specification Exception Material |
| SEM | Secure Ethernet Multiplexer |
| SEM | Service Element Management (Sprint) |
| SEM | Standard Electronic/Equipment Module |
| SEM | Survivability Evaluation Methodology |
| SEM | Supplier Engineering Memo |
| SEM | Synthetic Execution Model |
| SEM | Society for Experimental Methods |
| SEM | Synchronization Element Manager (Datum) |